Temperatura de polimerização da resina acrílica odontológica na medula espinhal de ratos

Abstract

The aim of this study was to examine if the polymerization temperature of the dental acrylic causes neurological signs and histological changes in rat spinal cord. Forty eight rats were divided in two groups: GI or bone cement (positive control) and GII or dental acrylic resin. Each group was divided in six subgroups according to the compound quantity (1 and 10 grams) length of postoperative period (24 and 72 hours) and local measurement of temperature (inside and outside the spinal canal). The bone cement or dental acrylic resin were molded and placed on the bony lamina and the dorsal spinous processes of vertebrae L1 and L2. Then the temperature of polimerization of the compound was measurement every 10 seconds. The maximum temperature of polymerization and the temperature difference between spinal canal internal and external were superior in subgroups that received 10 grams (p <0.05). The histological analysis of nerve tissue showed intensity variation of inflammatory reaction in the meninges in both groups (GI and GII), but more significant (p <0.05) in subgroups that received 10 grams of the compound. In the spinal cord parenchyma, there were alterations in GI and GII, with significant differences in length of postoperative period (p <0.05) between subgroups. There were not neurological deficits in the animals of this study. The results demonstrate that the polymerization temperature of dental acrylic resin in quantity of 1 or 10 grams causes histological changes in the spinal cord parenchyma and meninges, without neurological deficits in rats.