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Efeitos tóxicos do etanol e sua relação com o estresse oxidativo
(Universidade Federal de Santa Maria, 2005-08-12)
Ethanol is one of the most ingested substances among the different societies. So, it becomes target of several studies that intent to elucidate its mechanisms of toxicity. This study was aimed to better understand the link ...
Efeitos do disseleneto de difenila na atividade da enzima δ-aminolevulinato desidratase e em parâmetros bioquímicos de ratos com diabetes mellitus tipo 1
(Universidade Federal de Santa Maria, 2004-07-16)
The hyperglycemia and oxidative stress are factors strongly involved on development of many disorders that characterize the Diabetes Mellitus. It is known that some organic and inorganic selenium compounds are potent ...
Avaliação de parâmetros toxicológicos em piavas (Leporinus sp.) Expostas ao zinco e ao cobre
(Universidade Federal de Santa Maria, 2005-08-19)
The aim of this study was to verify the zinc and copper effects, metals frequently found in aquatic ecosystems, on the metabolism of piavas (Leporinus sp.). In this work, it was verified the average lethal concentrations ...
Efeito da diacereína sobre a febre induzida por suspensão de Saccharomyces cerevisiae e por prostaglandina e2 em ratos jovens
(Universidade Federal de Santa Maria, 2005-06-10)
Fever is a systemic response that results of a cascade of events that usually begins with pathogenic infection. Its development represents an important aspect of host defense that is mediated by the central nervous system. ...
Atividade da NTPDase, 5 -nucleotidase, acetilcolinesterase e níveis de peroxidação lipídica em ratos expostos ao cádmio e tratados com curcumina
(Universidade Federal de Santa Maria, 2014-10-15)
Cadmium (Cd) is one of the most toxic metals in relation to environmental contamination and human poisoning. This metal has a long biological half-life (10-30 years) and prolonged exposure to Cd has been associated with ...
Toxicidade do HgCl2 em ratas Wistar analisadas 12 e 48 horas após a exposição: possível efeito preventivo do zinco
(Universidade Federal de Santa Maria, 2016-02-10)
Mercury is a metal without any biological function. The exposure to mercury in any of different chemical forms can induce toxic effects on living organisms. This toxicity is commonly attributed to the high affinity that ...
Respostas bioquímicas em carpas (Cyprinus carpio) expostas ao fungicida tebuconazole (folicur® 200 ec)
(Universidade Federal de Santa Maria, 2010-07-22)
The intensive use and/or inadequate management of pesticides have led to contamination of the aquatic ecosystem, reaching the biota living there, including the fish. Pesticides can affect toxicological parameters these ...
Efeito antioxidante da creatina não protege da suscetibilidade à convulsões após traumatismo crânioencefálico em ratos
(Universidade Federal de Santa Maria, 2011-04-06)
Studies over recent years have highlighted the important role of creatine in health and in treating various neurological diseases. However, its role in secondary damage induced by traumatic brain injury (TBI) is not fully ...
Avaliação dos efeitos biológicos do (s) (3-feniltelanil propanamida) succinato de dimetila, um novo telúrio aminoácido derivado do ácido aspártico
(Universidade Federal de Santa Maria, 2011-03-25)
Recent studies from our group demonstrated that the (S)-dimethyl 2-(3-(phenyltellanyl) propanamido) succinate compound, a telluroamino acid showed glutathione peroxidase (GPx)-like activity, attesting to its antioxidant ...
Efeito da exposição in vivo ao ditelureto de difenila em camundongos: evidências para estresse oxidativo
(Universidade Federal de Santa Maria, 2010-09-24)
In this work, we investigated the effect of (PhTe)2 administration (10 μmol/kg and 50 μmol/kg) to adult mice on the behavioral performance and on some parameters of oxidative stress in the brain ad liver. The animals ...