Buscar
Itens para a visualização no momento 1-10 of 21
Atividade da NTPDase, 5 -nucleotidase, acetilcolinesterase e níveis de peroxidação lipídica em ratos expostos ao cádmio e tratados com curcumina
(Universidade Federal de Santa Maria, 2014-10-15)
Cadmium (Cd) is one of the most toxic metals in relation to environmental contamination and human poisoning. This metal has a long biological half-life (10-30 years) and prolonged exposure to Cd has been associated with ...
Efeito protetor do exercício físico nas alterações bioquímicas e cognitivas iniciais e tardias induzidas pelo traumatismo cranioencefálico em ratos
(Universidade Federal de Santa Maria, 2014-08-23)
Traumatic brain injury (TBI) is a major cause of morbidity and mortality in industrialized countries leading to the motor and cognitive deficits. Evidence demonstrated that exercise is neuroprotective in traumatic brain ...
N-acetilcisteína previne a piora da memória espacial induzida por ácido glutárico e lipopolissacarídio em ratos jovens
(Universidade Federal de Santa Maria, 2014-03-10)
Glutaric aciduria type I (GA-I) is an inborn error of metabolism (EIM) characterized biochemically by accumulation of glutaric acid (GA). The clinical manifestations are mainly neurological and develop during childhood. ...
Efetividade do (PhSe)2 em proteger contra a toxicidade do HgCl2
(Universidade Federal de Santa Maria, 2014-06-13)
Mercury (Hg) is a non-essential metal without biological function and also an environmental pollutant originating from various sources, especially from areas of mineral exploration and intense industrial activity. It is ...
Efeitos da VD3 sobre a memória e sobre o sistema purinérgico e colinérgico em um modelo de demência esporádica do tipo Alzheimer em ratos
(Universidade Federal de Santa Maria, 2014-06-13)
Alzheimer's disease (AD) is considered the main cause of dementia in elderly people worldwide. This disease affects the central nervous system (CNS), especially the cerebral cortex and hippocampus, areas that are responsible ...
Efeitos do consumo de sacarose sobre parâmetros metabólicos, desenvolvimentais e antioxidantes em Drosophila melanogaster: papel das plantas Syzygium cumini e Bauhinia forficata
(Universidade Federal de Santa Maria, 2014-03-14)
The fruit fly, Drosophila melanogaster, has been considered a suitable model organism for investigation of developmental/metabolic dysfunctions and therapeutic strategies. In this work Drosophila melanogaster larvae were ...
Envolvimento dos sistemas adenosinérgico e dopaminérgico no efeito antinociceptivo de um derivado do selenoesterol em modelos de nocicepção aguda em camundongos
(Universidade Federal de Santa Maria, 2014-08-01)
Pain is a complex, multifactorial and protective process essential to the preservation of the integrity of the organisms, but when it becomes persistent its presence is devastating, which considerably reduces the well-being ...
Envolvimento dos sistemas serotoninérgico e dopaminérgico na ação do tipo antidepressiva do 7-flúor-1,3 difenilisoquinolina-1-amino em camundongos
(Universidade Federal de Santa Maria, 2014-03-11)
Depression is a psychiatric disorder associated with a negative impact on quality of life. Monoaminergic system has been involved in this disease and in the action of antidepressants. This study aimed to investigate the ...
Avaliação dos efeitos farmacológico e toxicológico de 4- organocalcogeno-isoquinolinas
(Universidade Federal de Santa Maria, 2014-03-12)
Monoamine oxidase (MAO) is a target enzyme in the treatment of several
pathologies, being that new molecules which inhibit of a selective, potent and
reversible manner their isoforms and without adverse effects are ...
Caracterização físico-química do mel do bioma pampa brasileiro e estudo do seu potencial antioxidante in vitro e in vivo em modelo de Drosophila melanogaster
(Universidade Federal de Santa Maria, 2014-03-14)
Honey is a complex mixture produced by honey bees from the nectar, which is used by
its sweetening properties, as well as by its human health benefits. The aim of this study was to
characterize, for the first time in ...