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Efeito protetor do extrato de lingonberry sobre o sistema purinérgico e estresse oxidativos no sistema nervoso de ratos diabéticos
(Universidade Federal de Santa Maria, 2015-10-23)
Diabetes mellitus (DM) is considered a metabolic disorder that affects large part of worldwide. The hyperglycemia of diabetes cause cognitive impairments associated with physiological and structural changes in the central ...
Avaliação da atividade de enzimas que hidrolisam nucleotídeos e nucleosídeo de adenina em pacientes com melanoma cutâneo.
(Universidade Federal de Santa Maria, 2015-08-20)
The Cutaneous Melanoma (CM) is considered responsible for most deaths related to skin cancer. The frequency of new cases and incidence is increasing, especially among young people. In Brazil the highest rates are in the ...
Artemísia absinthium minimiza a toxicidade induzida por paracetamol em camundongos
(Universidade Federal de Santa Maria, 2015-09-22)
Acetaminophen is a popular analgesic associated with toxic ingestions. There are many studies about prevention of APAP induced hepatotoxicity including the medicinal plants. Artemisia absinthium (AA) is one of them, but ...
Efeitos do ácido gálico em parâmetros bioquímicos e de estresse oxidativo em ratos submetidos a um modelo experimental de diabetes
(Universidade Federal de Santa Maria, 2015-09-11)
Diabetes mellitus (DM) is a metabolic disorder characterized by hyperglycemia associated with the increase of free radicals and decrease in the antioxidant response. Gallic acid has many biological properties, among them ...
Mecanismos envolvidos na proteção do disseleneto de difenila sobre a toxicidade induzida por metilmercúrio em Saccharomyces cerevisiae
(Universidade Federal de Santa Maria, 2015-12-14)
Humans are usually exposed to organic form of mercury, the organometallic cation methylmercury ([CH3Hg]+, MeHg), by eating fish and seafood. The neurotoxic effects of MeHg are already widely known. Individuals exposed to ...
Avaliação dos mecanismos de toxicidade do disseleneto de difenila (PhSe)2 e cloreto de fenilselênio zinco (PhSeZnCl) em Saccharomyces cerevisiae
(Universidade Federal de Santa Maria, 2015-08-21)
Selenium (Se) is a microelement present in different animal tissues in the form of selenoproteins, for example, the glutathione peroxidase (GPx). Organic selenium compounds, such as diphenyl diselenide (PhSe)2 and fenilselenium ...
Exposição crônica ao herbicida paraquat promove desequilíbrio no sistema antioxidante e alterações comportamentais em peixe zebra (Danio rerio)
(Universidade Federal de Santa Maria, 2015-08-20)
In the last decade, it has been investigated behavioral patterns that may to reflect the physiological and biochemical changes in promising experimental models. Zebrafish (Danio rerio) is an useful tool for studying ...
Efeitos do laser sobre as alterações bioquímicas e morfológicas induzidas por um modelo de lesão cutânea em ratos
(Universidade Federal de Santa Maria, 2015-08-05)
Skin ulcer is a condition that can lead to serious complications, when not treated. Among the resources used to treat skin lesions is the low level laser therapy (LLLT), is extensively studied in the literature, wich could ...
Influência do exercício físico sobre parâmetros de dependência e recaída em ratos expostos à anfetamina: aspectos comportamentais e bioquímicos
(Universidade Federal de Santa Maria, 2015-02-10)
Amphetamine compounds and its derivatives are widely used in clinical medicine, but it is known that frames can cause dependence, tolerance and withdrawal. Furthermore, these drugs can alter metabolism and the functions ...
Influência do estresse em diferentes períodos iniciais da vida sobre o desenvolvimento de ansiedade e preferência por morfina em ratos
(Universidade Federal de Santa Maria, 2015-07-17)
Drug addiction has exerted a considerable impact on society, resulting in one of the biggest public health problems reaching different ethnic groups and social classes worldwide. Brazil is the largest consumer of opioid ...