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Avaliação dos efeitos de compostos orgânicos de selênio e de telúrio sobre a integridade estrutural e funcional de células sangüíneas humanas
(Universidade Federal de Santa Maria, 2009-01-09)
In view of the need to expand the toxicologic studies of organochalcogens in biological systems, the aim of this study was to investigate the effect of exposure to
organic compounds of selenium (Se) and tellurium (Te) on ...
Efeito inibitório do Ebselen, do disseleneto de difenila e do ditelureto de difenila sobre a atividade da LDH de mamíferos
(Universidade Federal de Santa Maria, 2009-02-09)
Ebselen is a seleno compound whose antioxidant properties have been
attributed to its thiol-peroxidase and thioredoxin-like activity: it decomposes
peroxides at the expense of reduced thiols. However, the excessive ...
Avaliação dos mecanismos envolvidos na ação antinociceptiva causada pelo seleneto vinílico bis substituído (SVBS) em camundongos
(Universidade Federal de Santa Maria, 2009-03-24)
The interest in organoselenium biochemistry and pharmacology has increased in the last two decades due to a variety of organoselenium compounds that possess biological activity. Accordingly, bis selenide is known as a safe ...
Atividade hipolipidêmica do disseleneto de difenila na hiperlipidemia induzida por Triton WR-1339 em camundongos
(Universidade Federal de Santa Maria, 2009-11-26)
In mammals, the liver plays a central role in whole-body lipid metabolism. Unfortunately, dysregulation of these pathways has been implicated in hyperlipidemias. In recent years, a significant association between the trace ...
Efeitos da exposição materna ou paterna ao disselento de difenila sobre o desenvolvimento intra-uterino da prole de ratas wistar
(Universidade Federal de Santa Maria, 2006-07-27)
Selenium (Se) is an essential trace element for man and is known for its role in regulating growth and development of the fetus and newborn. Furthermore, Se is a micronutrient required for normal spermatogenesis and, ...
Envolvimento do estresse oxidativo nas convulsões induzidas por disseleneto de difenila em ratos jovens
(Universidade Federal de Santa Maria, 2007-08-01)
Seizures can occur at any age, affecting at least 1-2% of the world population, they are far more common in children than adults. Prolonged seizures in the early developmental period can cause brain damage and lead to ...
Efeitos de compostos orgânicos de selênio sobre o desenvolvimento intra-uterino da prole de ratas wistar
(Universidade Federal de Santa Maria, 2007-12-03)
Selenium (Se) is an essential trace element for man and is known for its role in regulating growth and development of the fetus and newborn. It is well known that Se deficiency is related to miscarriages and pre-term ...
Avaliação dos efeitos do tratamento crônico com neurolépticos e sua interação com substâncias potencialmente antioxidantes sobre parâmetros de estresse oxidativo no fígado e rim de ratos
(Universidade Federal de Santa Maria, 2008-03-27)
Treatment with neuroleptic drugs has been associated to side effects like tardive diskynesia and hepatic damage. In spite of the several reports of hepatotoxicity after neuroleptic administration, few data are available ...
Efeito hepatoprotetor causado pelo 3-alquinil selenofeno contra o dano oxidativo induzido por agentes químicos em ratos
(Universidade Federal de Santa Maria, 2009-02-16)
The liver presents extraordinary functional diversity, particularly in the control of energy production, immune defense and volemic reserve. The human being is exposed
occupationally and in the environment to a variety ...