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Atividade anticonvulsivante do óleo de peixe
(Universidade Federal de Santa Maria, 2010-08-18)
Methylmalonic acidemias are inherited metabolic disorders characterized by methylmalonate (MMA) accumulation and neurological dysfunction, including seizures. Dietary fatty acids are known as an important energy source and ...
Ação protetora da Carya illinoensis sobre a toxicidade induzida por ciclofosfamida em ratos
(Universidade Federal de Santa Maria, 2010-01-29)
Cyclophosphamide (CP) is an alkylating agent widely used in anticancer and immunosuppression therapy. Like other chemotherapies, this drug can induce damage in healthy tissues, generating multiple organ toxicity. The study ...
Influência da temperatura na ação do fungo Duddingtonia flagrans utilizado como controle biológico de Haemonchus contortus em ovinos
(Universidade Federal de Santa Maria, 2010-05-28)
In recent years has increased the search for alternative methods to combat
gastrointestinal parasites, and in this context, biological control achieved by the fungus
Duddingtonia flagrans draws attention. In this study, ...
Traxoprodil atenua as convulsões induzidas por pentilenotetrazol
(Universidade Federal de Santa Maria, 2010-09-23)
There is evidence that while polyamines facilitate seizures by positively modulating N-methyl-D-aspartate receptors (NMDAr), selective antagonists of the NR2B-subunit decrease seizures. However, it remains undetermined ...
Contribuição do receptor vaniloide na nocicepção induzida pela injeção periférica de poliaminas em camundongos
(Universidade Federal de Santa Maria, 2010-12-02)
Polyamines (putrescine, spermidine and spermine) are important endogenous regulators of ion channels, such as vanilloid (TRPV1), glutamatergic (NMDA or AMPA/kainate) and acid-sensitive (ASIC) receptors. In the present ...
Efeitos da N-acetilcisteína sobre o dano oxidativo renal e hepático de ratos diabéticos
(Universidade Federal de Santa Maria, 2010-10-22)
Diabetes mellitus (DM) is a chronic disease characterized by hyperglycemia, which is related to oxidative stress and plays an important role in the development of other diseases and tissue damage, such as liver and kidney ...
Estudo da relação entre os níveis de indicadores biológicos de exposição ao tolueno e o estresse oxidativo em expostos ocupacionalmente a tintas
(Universidade Federal de Santa Maria, 2010-03-19)
Paints occupational exposure is an important health problem due to the wide variety of chemicals and xenobiotics present in their constitution. Organic solvents and heavy metals
are among the main chemical constituents ...
Creatina aumenta a atividade da Na+,K+-ATPase e previne o aparecimento das convulsões induzidas por pentilenotetrazol em ratos
(Universidade Federal de Santa Maria, 2010-02-26)
Creatine, an endogenous guanidino compound produced on liver, kidneys, pancreas, testes and brain, has been aim of several studies over the last years. Although most studies attribute the effects of creatine to their
energetic ...
Avaliação de biomarcadores inflamatórios e da atividade da adenosina deaminase e dipeptidil peptidase IV em linfócitos de pacientes com diabetes melito tipo 2
(Universidade Federal de Santa Maria, 2010-12-10)
Diabetes mellitus is a metabolic disease characterized by hyperglycemia due defective or deficient response to insulin secretion. Type 2 diabetes mellitus (Type 2 DM) is therefore associated with a general activation of ...
Alterações bioquímicas e estresse oxidativo associados ao hipotireoidismo
(Universidade Federal de Santa Maria, 2010-03-18)
Overt hypothyroidism is characterized by decreased of thyroid hormones synthesis,
with elevation of thyroid-stimulating hormone (TSH). It s a common disorder in
population with highest prevalence in women and with aging. ...