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Influência de produtos alimentícios ricos em fibra na biodisponibilidade de cádmio e de metais essenciais
(Universidade Federal de Santa Maria, 2009-12-21)
Dietary fibers can interfere in the bioavailability of mineral elements both negatively and positively. This has been the subject of several researches because there is a great interest in essential minerals; also, some ...
Efeitos protetores do zinco sobre alterações comportamentais e bioquímicas induzidas pelo mercúrio em ratos jovens
(Universidade Federal de Santa Maria, 2009-12-21)
Mercury is a toxic element that induces biochemical, neurological and behavioral changes, which can persist for a long time after the metal exposure. The contamination by mercury continues being a serious problem of public ...
Mecanismos envolvidos nos efeitos do seleneto vinílico bis substituído (svbs) em modelos animais de depressão e de dor
(Universidade Federal de Santa Maria, 2011-03-18)
The association between depression and chronic pain is frequent and bidirectional. The high number of patients with depression and chronic pain who are refractory to currently available drugs makes it important search for ...
A influência do processo inflamatório nas convulsões e no déficit cognitivo induzidos pelo ácido glutárico em ratos jovens
(Universidade Federal de Santa Maria, 2011-02-04)
Glutaric acidemia type I (GA-I) is an inborn error of metabolism (EIM), characterized biochemically by major accumulation of glutaric acid (GA) and pathologically by a characteristic striatal degeneration. The clinical ...
Avaliação toxicológica de compostos orgânicos de telúrio sobre o desenvolvimento pré-natal em camundongos
(Universidade Federal de Santa Maria, 2011-03-25)
It is known that most chemical agents readily cross the placenta and thus may be considered that maternal exposure to external agents can result in toxic effects on embryo-fetal organism. Considering the chemical characteristics ...
Estudo de mecanismos de toxicidade do metilmercúrio: papel protetor de flavonóides
(Universidade Federal de Santa Maria, 2010-08-12)
Methylmercury (MeHg) is an important environmental toxicant that may cause irreversible neurobehavioral and neuropsychological disorders in humans and experimental animals. The major mechanisms of MeHg-induced toxicity ...
Investigação da atividade antioxidante in vitro e da composição química de diferentes extratos de plantas medicinais
(Universidade Federal de Santa Maria, 2011-03-18)
Oxidative stress (OS) is involved in the development of several disorders involving the central nervous system, such as Alzheimer s disease (AD). Considering the limitations of current therapeutics for AD, there is still ...
Efeitos da crioterapia em modelos de contusão e isquemia/reperfusão sanguínea em músculo de ratos
(Universidade Federal de Santa Maria, 2010-12-16)
The musculoskeletal disorders are in the most common injuries observed in individuals in the primary care, occupational health, and in sports medicine. Among these disorders, the contusion is described as a direct traumatic ...
Atividade antioxidante e hepatoprotetora de plantas brasileiras, contendo compostos fenólicos.
(Universidade Federal de Santa Maria, 2010-06-07)
Plants from Brazilian flora were chosen and studied for their in vitro and in vivo antioxidant and in vivo hepatoprotetive activity, especially in relation to phenolic compounds which have several health benefits. These ...
Sistemas purinérgico e colinérgico e perfil oxidativo no encéfalo de roedores: influência do alumínio e de diferentes dietas
(Universidade Federal de Santa Maria, 2008-03-05)
In this study, the effects of Aluminium (Al) and of different diets, both individually and in association, were investigated through the determination of NTPDase, 5 -nucleotidase and acetylcholinesterase (AChE) activities ...