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Efeitos protetores do zinco sobre alterações comportamentais e bioquímicas induzidas pelo mercúrio em ratos jovens
(Universidade Federal de Santa Maria, 2009-12-21)
Mercury is a toxic element that induces biochemical, neurological and behavioral changes, which can persist for a long time after the metal exposure. The contamination by mercury continues being a serious problem of public ...
Ditelureto de difenila induz prejuízos no desenvolvimento, neurotoxicidade e desmielinização no sistema nervoso central de filhotes de ratos wistar
(Universidade Federal de Santa Maria, 2009-11-20)
The purpose of this study was to investigate if myelinogenesis is related to the mechanism by which diphenyl ditelluride [(PhTe)2] causes toxicity in rat pups. The present study was performed to examine whether the behavioral ...
Sensibilidade da enzima acetilcolinesterase (e.c. 3.1.1.7) à nicotina in vitro e in vivo
(Universidade Federal de Santa Maria, 2005-08-18)
This work valued the sensibility of the acetylcholinesterase from different sources and brain regions at nicotine in vitro, and the effects of the acute and subchronic exposures at the alkaloid on the brain acetylcholinesterase ...
Efeito do resveratrol nos sistemas colinérgico e purinérgico em encéfalo de ratos diabéticos
(Universidade Federal de Santa Maria, 2009-03-13)
Diabetes mellitus is a major public health problem throughout the world. Besides the most common complications in the peripheral nervous system, diabetes may also cause a series of cognitive, structural and functional ...
Avaliação de indicadores do estresse oxidativo e da atividade da enzima acetilcolinesterase sangüínea em pacientes com diagnóstico de acidente vascular cerebral isquêmico
(Universidade Federal de Santa Maria, 2006-09-29)
In ischemic stroke, damage to the brain is caused by a reduction or complete blockage of blood flow to parts of the brain, resulting in glucose and oxygen deficiency. It is a leading cause of mortality and disability ...
Atividade da acetilcolinsterase e da porfobilinogênio-sintase e alteração comportamental de ratos expostos à nicotina
(Universidade Federal de Santa Maria, 2007-03-16)
Tobacco smoking and nicotine replacement therapy are the main form of nicotine exposure. The drug abuse for humans often begins during adolescence and the exposure to nicotine during this phase produces long-term alterations, ...
Estudo do perfil oxidativo e atividade da enzima acetilcolinesterase em pacientes com leucemia linfoblástica aguda (lla)
(Universidade Federal de Santa Maria, 2008-01-28)
Acute lymphoblastic leukemia (ALL) is the most common cancer found in the pediatric population and is characterized by uncontrolled proliferation and maturation arrest of lymphoid progenitor cells (lymphoblasts) in the ...
Caracterização da atividade da enzima acetilcolinesterase de veneno de bungarus sindanus: estudos comparativos
(Universidade Federal de Santa Maria, 2008-03-10)
Acetylcholinesterase (AChE) belongs to a distinct family of serine hydrolases and is found in both synaptic and non-synaptic locations. At the synapses, it plays a major role
in the hydrolysis of the neurotransmitter ...