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Impacto do armazenamento a curto prazo e de múltiplos ciclos de congelamento/descongelamento sobre as concentrações séricas de ferro, ferritina e transferrina
(Universidade Federal de Santa Maria, 2020-08-07)
Most changes in laboratory results, despite all the care taken to eliminate or minimize
them, occur due to processes related to the pre-analytical phase. This stage may
suffer interference, such as: time and temperature ...
Fotoinativação de biofilmes de Pseudomonas aeruginosa utilizando porfirinas tetra-catiônicas
(Universidade Federal de Santa Maria, 2022-09-21)
Pseudomonas aeruginosa is an opportunistic pathogen that can be found in diverse
environments and is often associated with serious infections in immunocompromised patients.
This microorganism has a notorious ability to ...
Razões hematológicas em pacientes com covid-19 internados no Hospital Universitário de Santa Maria - RS
(Universidade Federal de Santa Maria, 2022-10-14)
The spread of the SARS-CoV-2 virus, which causes COVID-19, led to a global public
health emergency and the declaration of a pandemic by the WHO in 2020. It has been
demonstrated laboratory alterations in patients with ...
Desenvolvimento e estudo de estabilidade de suspensões de sulfadiazina para uso pediátrico
(Universidade Federal de Santa Maria, 2022-02-18)
Brazil is one of the countries with the highest prevalence of congenital toxoplasmosis in the
world and the treatment of the infection is done through the association of sulfadiazine (SDZ),
pyrimethamine and folinic acid. ...
Desenvolvimento de suspensões de nanocápsulas poliméricas contendo quercetina ou crisina e avaliação biológica em células B16F10 e em modelo de melanoma in vivo
(Universidade Federal de Santa Maria, 2020-01-24)
Studies have shown that the inflammatory process plays a relevant role in the development of cutaneous melanoma, moment when the immune response is critical, operating to control the development of this pathology and to ...
Efeito in vitro do ácido úrico sobre a frutosamina e HbA1c e impacto de diferentes condições de armazenamento sobre a frutosamina sérica
(Universidade Federal de Santa Maria, 2020-09-04)
Laboratory tests are influenced by factors, which can cause errors in the analyte dosage.
Among the main ones are the interference of several substances, such as uric acid, and the
inadequate storage of the samples. ...
Frequência da mutação JAK2V617F em pacientes com trombocitose no interior do RS
(Universidade Federal de Santa Maria, 2020-03-06)
Myeloproliferative neoplasms (MPN) are unique hematopoietic stem-cell disorders, resulting in an
increased proliferation of single or multilineage mature hematopoietic cells. JAK2V617F mutation is a
diagnostic ...
Redirecionamento de dexametasona e diclofenaco e efeito sinérgico com ácido nalidíxico, ciprofloxacino e vancomicina frente a Enterococcus spp.
(Universidade Federal de Santa Maria, 2022-03-23)
The spread of multi-antibiotic resistant bacteria (MDR) has compromised the available
therapeutic arsenal. Thus these MDR pathogens have become a public health problem
resulting in high morbidity and mortality rates. As ...
Atividade antimicrobiana, sinérgica e antibiofilme de sildenafil frente a Pseudomonas aeruginosa
(Universidade Federal de Santa Maria, 2021-03-29)
The increase in antimicrobial resistance has made the therapeutic armamentarium against bacterial infections increasingly scarce, generating a serious public health problem, especially in the hospital environment. In this ...
Avaliação de metodologia para análises in silico de dados de sequenciamento de genoma total de Klebsiella pneumoniae resistente a carbapenêmicos
(Universidade Federal de Santa Maria, 2021-10-14)
The emergence of Klebsiella pneumoniae strains resistant to different antimicrobial classes has
increased the concern regarding control and monitoring measures for this microorganism.
Whole Genome Sequencing (WGS) has ...