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Constituintes de Senecio platensis Arech. isolamento, elucidação estrutural e avaliação da atividade antibacteriana
(Universidade Federal de Santa Maria, 2007-11-09)
The genus Senecio (Asteraceae) constitutes a group of cosmopolitan plants formed by more than 2000 species. Although most of these plants are considered to be toxic due to the presence of pyrrolizidine alkaloids, several ...
Glechon spathulata Benth.: estudo fitoquímico e biológico
(Universidade Federal de Santa Maria, 2007-07-20)
The main groups of secondary metabolites of Glechon spathulata Benth. were
evaluated by a phytochemical screening and the volatile oil obtained by
hydrodistillation was analyzed by GC-MS. Volatile oil, ethanolic crude ...
Desenvolvimento e validação de métodos para determinação de tacrolimus em cápsulas
(Universidade Federal de Santa Maria, 2007-03-08)
Tacrolimus is a lactone macrolide, derived from Streptomyces tsukubaensis. It is an immunosuppressive drug that has been used in the prevention of organs transplant rejection, such as liver, kidney, heart, small intestine, ...
Diacereína: desenvolvimento e validação de métodos de quantificação e dissolução
(Universidade Federal de Santa Maria, 2007-03-15)
Diacerhein (DAR) is a slow acting symptomatic drug used to treatment of osteoarthritis. It is available in the Brazilian market as capsules and compounded capsules. There are no
official methods for DAR analysis in any ...
Relação entre a suscetibilidade de Candida spp a anfotericina B, com óbito ou sobrevivência dos pacientes em episódios de candidemia
(Universidade Federal de Santa Maria, 2007-01-22)
Among fungal infections, those caused by Candida spp are the most recurrent. Candidaemias are the most emergent and amphotericin B has been the mainstay of therapy in spite of its therapeutic failures. Because of these ...
Avaliação da albumina modificada pela isquemia na anemia associada à doença renal crônica
(Universidade Federal de Santa Maria, 2007-12-19)
Chronic kidney disease (CKD) is highly prevalent, with increasing numbers of patients affected by the disease world-wide, and anemia is a common finding in patients with CKD. Anemia impacts negatively on cardiovascular ...
Sibutramina: validação de metodologia e avaliação biofarmacotécnica
(Universidade Federal de Santa Maria, 2007-08-17)
Sibutramine is therapeutically classified as an anorexigen, being recommended for obesity treatment and reduction of body weight, combined with diet and exercises. Its expected activity is the weight loss through inhibiting ...
Azitromicina: desenvolvimento e validação de métodos de análise em formas farmacêuticas
(Universidade Federal de Santa Maria, 2007-05-04)
Azithromycin (AZ) is a macrolide antibiotic derivate from erytromycin. AZ has a broad spectrum of activity against common gram-negative pathogens and has been used for the treatment of respiratory tract infection, skin ...
Constituintes de Senecio heterotrichius DC.: isolamento, elucidação estrutural, derivatização e avaliação da atividade antimicrobiana; estudo dos constituintes voláteis de outras espécies de senecio
(Universidade Federal de Santa Maria, 2007-03-05)
Genus Senecio (Asteraceae) constitutes a group of cosmopolitan plants formed by more than 2000 species. Although these plants have toxicity recognized due to the presence of pyrrolizidine alkaloids, several of them are ...
Suscetibilidade de Candida spp. resistentes e sensíveis ao fluconazol frente a óleos essenciais extraídos de condimentos
(Universidade Federal de Santa Maria, 2007-03-23)
In the present study, it was assessed antifungal activity of different essential oils obtained from plants traditionally used as condiments, against Candida isolates proven to be susceptible and resistant to the antifungal ...