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Itens para a visualização no momento 11-20 of 51
Otimização e validação da quantificação de malondialdeído plasmático por cromatografia líquida de alta eficiência com detecção visível
(Universidade Federal de Santa Maria, 2007-03-06)
The overproduction of reactive oxygen and nitrogen species or the reduction in the antioxidant capacity results in the oxidative stress. The lipid peroxidation involves the oxidative deterioration of polyunsaturated fatty ...
Desenvolvimento e validação de metodologia para avaliação de rupatadina por cromatografia líquida e eletroforese capilar
(Universidade Federal de Santa Maria, 2009-03-12)
Rupatadine is a second generation antihistamine H1, from the pyperidinic group, which inhibits both the histamine and platelet activating factor effects, and is clinically used for the treatment of allergic rhinitis and ...
Identificação de bacilos Gram positivos aeróbicos isolados de espécimes clínicos em um hospital escola
(Universidade Federal de Santa Maria, 2007-03-09)
In recent years, the gram positive rods have been reported with an increasing frequency as nosocomial pathogens. The recognition those microorganisms as etiological agents
of serious infections, such as bacterial sepsis, ...
Triazenos: clivagem do DNA, atividade antibacteriana e toxicidade frente à Artemia salina Leach
(Universidade Federal de Santa Maria, 2007-12-13)
In this work, six triazene compounds are assayed to DNA cleavage activity. The same six triazenes and the drug Asercit® (dacarbazine) are assayed to antibacterial activity and toxicity to Artemia salina Leach.: ...
Desenvolvimento e validação de metodologias para avaliação de ezetimiba por cromatografia líquida e espectrometria de massas
(Universidade Federal de Santa Maria, 2007-03-30)
Ezetimibe selectively inhibits the intestinal absorption of dietary cholesterol and related plant sterols, from the 2-azetidinones group, and is used for the treatment of
hypercholesterolemia and phytosterolemia. The ...
Estudo de métodos cromatográficos para avaliação de potência de filgrastima e correlação com ensaio biológico
(Universidade Federal de Santa Maria, 2006-06-23)
The granulocyte-colony stimulating factor (G-CSF) is a hematopoietic cytokine that stimulates and regulates the proliferation and differentiation of neutrophil precursor cells of the bone marrow. The recombinant hormone ...
Bezafibrato: validação de metodologia e aplicação em estudo farmacocinético de formulações farmacêuticas
(Universidade Federal de Santa Maria, 2007-10-11)
Fibrates constitute an important class of drugs used in the treatment of the
dyslipidemia, which is the main risk factor for the aterosclerosis development and
incidence of cardiovascular diseases. The present dissertation ...
Suscetibilidade in vitro de Sporothrix schenckii e avaliação da antifungicoterapia na esporotricose experimental em modelo murino
(Universidade Federal de Santa Maria, 2008-03-19)
The approval of the protocol M-38A by Clinical and Laboratory Standards Institute
(CLSI), which established standardized procedures for the evaluation of the in vitro
susceptibility of moulds, has expanded the inherent ...
Constituintes de Senecio platensis Arech. isolamento, elucidação estrutural e avaliação da atividade antibacteriana
(Universidade Federal de Santa Maria, 2007-11-09)
The genus Senecio (Asteraceae) constitutes a group of cosmopolitan plants formed by more than 2000 species. Although most of these plants are considered to be toxic due to the presence of pyrrolizidine alkaloids, several ...
Avaliação de marcadores inflamatórios e antígenos ABO em pacientes com diagnóstico de câncer de próstata
(Universidade Federal de Santa Maria, 2008-06-20)
Prostate cancer (PC) is a disease in men and became the first cause of death by
cancer in Brazil. The carcinogenesis is related to the presence of local inflammatory
process and to the loss of blood group in neoplasic ...