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Desenvolvimento e validação de metodologias analíticas para determinação do itraconazol matéria-prima e cápsulas
(Universidade Federal de Santa Maria, 2008-05-13)
Itraconazole is a triazole antifungical agent with a broad spectrum of activity belonging to the class of azole, indicated in the treatment of different types of mycotic infections systemic and local. Its mechanism of ...
Desenvolvimento e validação de metodologia para avaliação de fluticasona por cromatografia líquida e eletroforese capilar
(Universidade Federal de Santa Maria, 2009-03-24)
Fluticasone propionate (FP) is a synthetic glucocorticoid with potent anti-inflammatory activity that has been effectively used for the treatment of seasonal and allergic perennial rhinitis, minimizing systemic activity. ...
Glechon spathulata Benth.: estudo fitoquímico e biológico
(Universidade Federal de Santa Maria, 2007-07-20)
The main groups of secondary metabolites of Glechon spathulata Benth. were
evaluated by a phytochemical screening and the volatile oil obtained by
hydrodistillation was analyzed by GC-MS. Volatile oil, ethanolic crude ...
Desenvolvimento e validação de métodos para avaliação de cloridrato de fexofenadina
(Universidade Federal de Santa Maria, 2006-03-31)
The fexofenadina is an antihistamine non sedative that acts as antagonistic selective in the outlying receivers H1 of the histamine, being used in the symptomatic treatment of allergic manifestations as medication of first ...
Prevalência das famílias TEM, SHV e CTX-M de β-lactamases de espectro entendido em Escherichia coli e Klebsiella spp. no Hospital Universitário de Santa Maria, Rio Grande do Sul
(Universidade Federal de Santa Maria, 2009-10-08)
Extended-spectrum β-lactamases (ESBLs) are plasmid-mediated bacterial enzymes that confer resistance for most β-lactams antibiotics. These enzymes are widespread
in microorganisms in hospital settings worldwide. This study ...
Desenvolvimento e validação de metodologia analítica para avaliação de ebastina comprimidos
(Universidade Federal de Santa Maria, 2009-03-26)
Ebastine is a second generation antihistaminic drug used to treat allergic rhinitis and urticaria. It is available in the Brazilian market as tablets and syrup. There are no official methods for ebastine analysis in ...
Desenvolvimento e validação de metodologia para avaliação de rimonabanto e estudo da sua dissolução a partir de formas farmacêuticas
(Universidade Federal de Santa Maria, 2009-12-15)
Rimonabant is a selective antagonist of the cannabinoid type 1 (CB1) receptor
indicated as an adjunct to diet and exercise for the treatment of obese patients (BMI ≥ 30
kg/m2), or overweight patients (BMI > 27 kg/m2) ...
Estudo químico e biológico de Conyza bonariensis (L.) Cronquist (Asteraceae)
(Universidade Federal de Santa Maria, 2006-06-09)
Conyza bonariensis (L.) is a native plant of South America, easily found in the south area. It s popular name is buva or margaridinha-do-campo. This plant is very used in folk medicine for rheumatism, gout, cystitis, ...
Desenvolvimento e validação de metodologia para análise de besilato de anlodipino em formas farmacêuticas
(Universidade Federal de Santa Maria, 2005-04-25)
In this work the quantitative methodologies for determination of amlodipine besilate in tablets and capsules were validated. The methods used for drug determination were: liquid chromatography (LC) and ultraviolet ...
Desenvolvimento e validação de métodos para determinação de tacrolimus em cápsulas
(Universidade Federal de Santa Maria, 2007-03-08)
Tacrolimus is a lactone macrolide, derived from Streptomyces tsukubaensis. It is an immunosuppressive drug that has been used in the prevention of organs transplant rejection, such as liver, kidney, heart, small intestine, ...