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Investigação da contaminação bacteriana em concentrados plaquetários e avaliação de técnicas convencionais
(Universidade Federal de Santa Maria, 2012-01-06)
Blood transfusions have always been great support for monitoring the treatment of cancer, especially patients in the sectors of hematology-oncology, but still stand out as a major source of transmission of infectious ...
Determinação de parâmetros físico-químicos, atividade anti-inflamatória e antimicrobiana de Morus Alba L. (Moraceae)
(Universidade Federal de Santa Maria, 2012-03-16)
The Moraceae family consists of approximately 1000 species, distributed in 61 genera. Morus alba has small flowers, simple stems up to 33 feet tall and whole leaves, serrated or lobed, fruit September to November. M. alba ...
Elettaria cardamomum: caracterização, toxicidade, atividade antimicrobiana e sinérgica do óleo essencial frente a Aeromonas hydrophila
(Universidade Federal de Santa Maria, 2021-03-29)
Characterized as being Gram-negative bacteria, Aeromonas species can cause several infections,
which include urinary tract infections, pneumonia, meningitis, sepsis, among others. Drugs such as
Florfenicol (FFC) and ...
Desenvolvimento e validação de um método automatizado para a quantificação dos níveis séricos de nitrito/nitrato
(Universidade Federal de Santa Maria, 2012-03-09)
Nitric oxide (NO) is a reactive free radical, acting as a messenger molecule, mediating several functions, including vasodilation, platelet aggregation inhibition and neurotransmission. Because this radical to have a short ...
Desenvolvimento e estudo de estabilidade de suspensões de pirimetamina para uso pediátrico
(Universidade Federal de Santa Maria, 2023-03-27)
Toxoplasmosis is a zoonosis with worldwide distribution, which can be transmitted to the
fetus during pregnancy. The child's treatment should start just after birth and consists of
pyrimethamine (PYM), sulfadiazine, and ...
Nanoesferas poliméricas mucoadesivas associadas aos ácidos cafeico e ferúlico: caracterização, estudo de estabilidade, potencial antioxidante e segurança
(Universidade Federal de Santa Maria, 2023-07-05)
Oral mucositis is characterized by the appearance of erythematous and ulcerative lesions in the oral
cavity induced by chemotherapies and radiotherapies, that damage on basal layer of the tissues lead to
the expression ...
Avaliação do perfil oxidativo e inflamatório na infecção por Influenza B
(Universidade Federal de Santa Maria, 2023-08-10)
The influenza B virus, the causative agent of influenza, is still one of the main causes of
respiratory diseases that affects the world's population and causes thousands of deaths
worldwide. Oxidative stress, may be ...
Monitoramento terapêutico do 5-fluorouracil como ferramenta clínica de avaliação no tratamento de pacientes com câncer do trato gastrointestinal
(Universidade Federal de Santa Maria, 2023-07-21)
5-fluorouracil (5-FU) is an essential part of the treatment of numerous solid cancers, especially
of the gastrointestinal tract (GI tract). Despite the many advances related to its use, some
patients undergoing 5-FU ...
Potenciais impactos da carbamilação in vitro sobre a atividade da proteína C, proteína S e antitrombina
(Universidade Federal de Santa Maria, 2023-08-29)
Hemostasis is a vital process in the body that aims to maintain the balance between the
procoagulant and anticoagulant systems. An imbalance in this system can cause uncontrolled
bleeding or thrombotic events. For the ...
Nanocápsulas contendo ácido ferúlico: desenvolvimento, avaliação da segurança e citoproteção em células mononucleadas humanas
(Universidade Federal de Santa Maria, 2020-01-16)
Ferulic acid is a phenolic compound that has antioxidant, anti-inflammatory and
anticarcinogenic properties. However, it has limited oral bioavailability, challenging its
therapeutic application. ...