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Desenvolvimento e estudo de estabilidade de suspensões de pirimetamina para uso pediátrico
(Universidade Federal de Santa Maria, 2023-03-27)
Toxoplasmosis is a zoonosis with worldwide distribution, which can be transmitted to the
fetus during pregnancy. The child's treatment should start just after birth and consists of
pyrimethamine (PYM), sulfadiazine, and ...
Nanoesferas poliméricas mucoadesivas associadas aos ácidos cafeico e ferúlico: caracterização, estudo de estabilidade, potencial antioxidante e segurança
(Universidade Federal de Santa Maria, 2023-07-05)
Oral mucositis is characterized by the appearance of erythematous and ulcerative lesions in the oral
cavity induced by chemotherapies and radiotherapies, that damage on basal layer of the tissues lead to
the expression ...
Avaliação do perfil oxidativo e inflamatório na infecção por Influenza B
(Universidade Federal de Santa Maria, 2023-08-10)
The influenza B virus, the causative agent of influenza, is still one of the main causes of
respiratory diseases that affects the world's population and causes thousands of deaths
worldwide. Oxidative stress, may be ...
Monitoramento terapêutico do 5-fluorouracil como ferramenta clínica de avaliação no tratamento de pacientes com câncer do trato gastrointestinal
(Universidade Federal de Santa Maria, 2023-07-21)
5-fluorouracil (5-FU) is an essential part of the treatment of numerous solid cancers, especially
of the gastrointestinal tract (GI tract). Despite the many advances related to its use, some
patients undergoing 5-FU ...
Potenciais impactos da carbamilação in vitro sobre a atividade da proteína C, proteína S e antitrombina
(Universidade Federal de Santa Maria, 2023-08-29)
Hemostasis is a vital process in the body that aims to maintain the balance between the
procoagulant and anticoagulant systems. An imbalance in this system can cause uncontrolled
bleeding or thrombotic events. For the ...
Hidrogéis e filmes nanocompósitos de polissacarídeos contendo substâncias do gergelim para o tratamento de doenças vaginais
(Universidade Federal de Santa Maria, 2023-10-06)
Trichomoniasis and cervical cancer are gynecological diseases relevant to public health. This
study focused on researching new potential therapeutical agents and improving the
pharmaceutical dosage forms used for their ...
Atividade antimicrobiana, antibiofilme e citotoxicidade do óleo essencial de Thymus vulgaris com ênfase em biofilmes de Pseudomonas aeruginosa
(Universidade Federal de Santa Maria, 2023-05-08)
Biofilms are characterized as a set of microorganisms surrounded by a matrix of
extracellular polysaccharides. Pseudomonas aeruginosa is a Gram negative bacillus,
which expresses several virulence factors. The ability ...
Avaliação da atividade antimicrobiana, antibiofilme e citotoxicidade do óleo essencial de Cymbopogon martinii frente a Staphylococcus aureus
(Universidade Federal de Santa Maria, 2023-05-10)
The biofilm is characterized as a community of microorganisms adhered to a surface,
which gives microbial cells protection against external agents, characterizing itself as
an important form of resistance. In hospitals, ...
Caracterização das estratégias diagnósticas adotadas no período de pandemia por SARS-CoV-2: uma perspectiva epidemiológica
(Universidade Federal de Santa Maria, 2023-12-20)
The emergence of the SARS-CoV-2 virus in late 2019 triggered a global health crisis, leading
to the World Health Organization (WHO) declaring a pandemic in March 2020. The rapid
spread of the virus and the emergence of ...