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Itens para a visualização no momento 11-20 of 38
Propriedades de proteção gastrointestinal da Rosmarinus officinalis l. em associação a testes microbiológicos e antioxidantes in vitro e ex vivo
(Universidade Federal de Santa Maria, 2016-03-18)
The elevate production of reactive species over physiological levels and associated to pathogenic bacteria could
represent a high risk for many diseases. The high levels of oxidative stress and inflammation can be present ...
Ação protetora da Carya illinoensis sobre a toxicidade induzida por ciclofosfamida em ratos
(Universidade Federal de Santa Maria, 2010-01-29)
Cyclophosphamide (CP) is an alkylating agent widely used in anticancer and immunosuppression therapy. Like other chemotherapies, this drug can induce damage in healthy tissues, generating multiple organ toxicity. The study ...
Efeito da (+)-catequina sobre adiscinesia orofacial induzida por reserpina em camundongos e atividade damonoaminoxidase
(Universidade Federal de Santa Maria, 2018-03-20)
Tardive dyskinesia (TD) is a disabling and debilitating disorder due to the chronic use of antipsychotics that affects around 20% to 50% of patients. It is characterized by involuntary, repetitive and abnormal movements ...
JM-20 como composto multialvo: avaliação do potencial antioxidante, inibidor de colinesterases e citotoxicidade
(Universidade Federal de Santa Maria, 2020-10-29)
Multi-target compounds have aroused the interest of many researchers. The main characteristic of these substances is the ability to act through different mechanisms of action, a relevant fact in cases of pathologies caused ...
Neuroproteção do cassis (Ribes nigrum L.) e de sua associação com o Donepezil em modelo de amnésia induzida por escopolamina
(Universidade Federal de Santa Maria, 2019-12-13)
Memory deficits that occur with the process of aging could also be associated with the pathophysiology of neurodegenerative diseases, such as Alzheimer’s disease (AD). AD is characterized by the progressive deterioration ...
Avaliação da capacidade antioxidante in vitro de novos compostos mono e disseleneto
(Universidade Federal de Santa Maria, 2013-07-26)
The antioxidant action of organic selenium compounds, as well as ebselen and diphenyl diselenide (DPDS), is closely connected to its ability of generating the selenol group. (In) this study it was evaluated the in vitro ...
Estudo das propriedades antioxidantes de diferentes ftalocianinas
(Universidade Federal de Santa Maria, 2013-02-22)
Oxidative stress is believed to be involved in the etiology of several chronic diseases, including cardiovascular disease, diabetes, cancer, and neurodegenerative disorders. From this perspective, we have evaluated the ...
Efeito protetor do extrato hidroalcoólico de própolis marrom nas lesões vaginais induzidas pelo herpes simples vírus tipo 2
(Universidade Federal de Santa Maria, 2013-01-25)
Propolis is a natural compound and has been highlighted for its antioxidant, antiinflammatory
and antiviral properties. The purpose of this study was to investigate if
brown hydroalcoholic propolis extract (HPE) protects ...
Síntese e atividades antioxidante e antitumoral de 5´-arilseleno azidotimidina
(Universidade Federal de Santa Maria, 2012-03-30)
The synthesis of compounds that use a nucleoside as the base structure, has an intense field application. Among these compounds, the most known nowadays is azydothymidine or zidovudine, a drug which was first synthesized ...
Efeito antioxidante de uma nova classe de compostos teluroacetilenos: estudos in vitro e in vivo
(Universidade Federal de Santa Maria, 2010-04-01)
Organotellurium compounds have been reported as antioxidants in several models of oxidative stress, especially in the brain. This study investigated the effect of telluroacetylenes a-d on pharmacological assays in vitro. ...