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Sensibilidade da enzima acetilcolinesterase (e.c. 3.1.1.7) à nicotina in vitro e in vivo
(Universidade Federal de Santa Maria, 2005-08-18)
This work valued the sensibility of the acetylcholinesterase from different sources and brain regions at nicotine in vitro, and the effects of the acute and subchronic exposures at the alkaloid on the brain acetylcholinesterase ...
A inibição da enzima δ-aminolevulinato desidratase por monossacarídeos não é mediada pela oxidação de grupos -sh
(Universidade Federal de Santa Maria, 2004-08-18)
Heme pathway enzyme δ-aminolevulinate dehydratase (δ-ALA-D) is a good marker for oxidative stress and metal intoxication. This sulfhydrylic enzyme is inhibited in several oxidative pathologies like lead, mercury and aluminum ...
Quantificação da glutationa reduzida em eritrócitos humanos por cromatografia líquida de alta eficiência-uv: validação e aplicação
(Universidade Federal de Santa Maria, 2005-02-21)
Oxidative stress may be initiated by a decline in the antioxidant defence system or by an overproduction of free radicals leading to an imbalance between oxidants and antioxidants. The most significant alteration in the ...
Derivados pirazolínicos inéditos causam antinocicepção em camundongos no teste da formalina
(Universidade Federal de Santa Maria, 2004-07-29)
The discovery of pyrazole derivatives dates back to 1884, when the German chemist Ludwig Knorr attempted to synthesize quinoline derivatives with antipyretic activity and accidentally obtained antipyrine, a pyrazolinone, ...
Efeito teratogênico do ditelureto de difenila, administrado durante a gestação em ratas e efeito de organocalcogênios sobre a reprodução em ratos machos
(Universidade Federal de Santa Maria, 2004-07-30)
Organochalcogens are important intermediates and the main applied reagents in organic synthesis and in industrial processes, which can increase human exposure risk to these chemicals in the workplace. The effects of single ...
O envolvimento de proteínas quinases na facilitação do aprendizado espacial induzido por creatina
(Universidade Federal de Santa Maria, 2009-11-20)
Decline cognitive related to neurodegenerative diseases are very commom in patients, probably in function of aging. Since there are few effectives therapeutics
approaches to loss memory treatment, but studies about new ...
Perfil lipídico de pacientes ambulatoriais de Salvador do Sul, RS
(Universidade Federal de Santa Maria, 2005)
Efeito do resveratrol nos sistemas colinérgico e purinérgico em encéfalo de ratos diabéticos
(Universidade Federal de Santa Maria, 2009-03-13)
Diabetes mellitus is a major public health problem throughout the world. Besides the most common complications in the peripheral nervous system, diabetes may also cause a series of cognitive, structural and functional ...
Efeito do exercício agudo de curta duração na atividade da enzima δ-aminolevulinato desidratase em humanos
(Universidade Federal de Santa Maria, 2009-02-27)
Aerobic exercise of sufficient intensity and duration can result in increased generation of reactive oxygen species and exercise of extreme endurance may cause oxidative stress with a concomitant decreased activity of ...
O complexo metilmercúrio-cisteína altera o acúmulo de mercúrio em diferentes tecidos de camundongo
(Universidade Federal de Santa Maria, 2009-03-26)
Methylmercury (MeHg) is related to several deleterious effects on the vertebrate tissues, mainly on central nervous system, and part of these effects are through of interaction with sulfhydryl group found in cellular ...