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Avaliação da atividade de ectonucleotidases e acetilcolinesterase em ratos expostos à fumaça de cigarro e nicotina
(Universidade Federal de Santa Maria, 2012-01-30)
Cigarette smoke is a serious health problem and the most important cause of avoidable death
in the world. It has a complex mixture with more than 4700 constituents, including nicotine and
reactive oxygen species (ROS). ...
Avaliação do potencial efeito antidepressivo do 2-BFI, ligante imidazolínico I2, em camundongos
(Universidade Federal de Santa Maria, 2012-03-02)
Depression is a complex, chronic and disabling psychiatric disease that carries
a high social cost. Among the various classes of antidepressants are the monoamine
oxidase A (MAO-A) inhibitors that reduce monoamine ...
Desenvolvimento e validação de um método automatizado para a quantificação dos níveis séricos de nitrito/nitrato
(Universidade Federal de Santa Maria, 2012-03-09)
Nitric oxide (NO) is a reactive free radical, acting as a messenger molecule, mediating several functions, including vasodilation, platelet aggregation inhibition and neurotransmission. Because this radical to have a short ...
Seleção de conteúdos e diferentes recursos didáticos no ensino fundamental: análise utilizando o tema visão
(Universidade Federal de Santa Maria, 2016-06-03)
This research investigated how science teachers from public schools select topics for teaching the subject the human eye and which teaching resources they used. The second part of the research analyzed the conceptions ...
Envolvimento das poliaminas no ataque agudo de gota em camundongos
(Universidade Federal de Santa Maria, 2016-02-26)
Gout attack is characterized severe joint pain and inflammation with concomitant accumulation of monosodium urate (MSU) crystals. However, gout and the mechanisms responsible for the acute attacks are poorly understood, ...
Emprego do óleo de Borago officinalis L. no desenvolvimento de formulações semissólidas e nanocápsulas poliméricas destinadas ao tratamento tópico de doenças inflamatórias da pele
(Universidade Federal de Santa Maria, 2014-04-28)
This study aimed to obtain semisolids formulations and lipid core nanocapsules containing borage oil associated or not with betamethasone dipropionate, for their application in the treatment of atopic dermatitis. A gel-cream ...
Receptores EP1 E EP3 modulam as crises epilépticas induzidas por pentilenotetrazol e ácido caínico em camundongos
(Universidade Federal de Santa Maria, 2013-06-27)
Epilepsy is one of the most common neurologic disorders. It has been suggested that
seizures may be facilitaded by inflammation. PGE2 is one of the most important inflammatory
mediators, and facilitates pentylenetetrazol ...
Propriedades antitumorais do açaí (Euterpe oleracea, Mart., 1824) e avaliação do desbalanço oxidativo relacionado ao genótipo da SOD2 em células saudáveis
(Universidade Federal de Santa Maria, 2019-08-28)
Cancer is one of the main problems of public health worldwide, and in most cases occurs in cells of epithelial origin, since they have a high proliferative rate and have limited characteristics of cell senescence. These ...
Influência da modulação monoaminérgica sobre comportamentos nociceptivos térmicos de Drosophila melanogaster
(Universidade Federal de Santa Maria, 2018-08-17)
Drosophila melanogaster is an model organism that have been used to research molecular mechanisms and role of the genes and proteins involved in nociception, which have a function in detect noxious stimuli and protect the ...
Toxicidade de organocalcogênios e seus mecanismos através da expressão gênica em leucócitos humanos
(Universidade Federal de Santa Maria, 2015-02-06)
Selenium (Se) is an essential micronutrient present in selenoproteins on living beins, in the form of the amino acid selenocysteine and selenomethionine. Chemically related to Se, tellurium (Te) has no biological function ...