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Efeitos comportamentais e endócrinos da exposição na fase embrionária ao etonogestrel em peixe-zebra
(Universidade Federal de Santa Maria, 2023-09-18)
Improper disposal of expired drugs directly into the garbage or sewage systems
without specific treatment increases concentration of these components in wastewater.
Waste from pharmaceutical industries, used in research ...
Prescrição de fármacos inapropriados em idosos hospitalizados: análise da mortalidade e sobrevida
(Universidade Federal de Santa Maria, 2023-09-29)
Introduction: Elderly people (>60 years old) have a high prevalence of chronic noncommunicable diseases (DCNTs), often managed through the daily use of four or more
drugs (polypharmacy). Furthermore, they may present ...
Efeito de diferentes protocolos de treinamento físico em modelo experimental de osteoartrite
(Universidade Federal de Santa Maria, 2023-09-21)
Osteoarthritis is characterized as a chronic and degenerative joint disease, affecting
approximately 50% of the elderly population, being associated with pain and morphological
and biochemical alterations. It is known ...
Avaliação fármaco-toxicológica da molécula JM-20 em Caenorhabditis elegans
(Universidade Federal de Santa Maria, 2023-10-17)
With the discovery of new molecules with pharmaceutical potential, studies examining different mechanisms of action and toxicological aspects emerge. The 3-ethoxycarbonyl-2-methyl-4-(2-nitrophenyl)-4,11-dihydro-1H-pyrido ...
Avaliação da influência da dieta em parâmetros de estresse oxidativo, inflamação e modificações epigenéticas em pacientes com lúpus eritematoso sistêmico
(Universidade Federal de Santa Maria, 2023-10-11)
Exacerbated cellular activation due to autoimmunity in Systemic Lupus Erythematosus (SLE)
can generate an imbalance between antioxidants and pro-oxidants, triggering oxidative stress.
In addition to oxidative stress, ...
Curva dose-resposta do extrato lipofílico composto por clorofilas e carotenoides da microalga Scenedesmus obliquus: papel oxidativo e envolvimento da sinalização purinérgica
(Universidade Federal de Santa Maria, 2023-09-27)
More and more innovative proposals based on bioactive compounds are being presented to
the public. The use of microalgae, such as the species Scenedesmus obliquus, has played
an interesting role in this regard through ...
Efeitos do esteróide anabolizante associado ao exercício físico resistido em parametros bioquímicos, inflamatórios e neuroquímicos em ratas
(Universidade Federal de Santa Maria, 2023-09-29)
Regular physical exercise is the best strategy for maintaining a healthy body and autonomous aging. However, in recent years the search for the perfect body has contributed to the search for anabolic resources that accelerate ...
Avaliação da toxicidade de pesticidas sobre o crescimento e biomarcadores de estresse oxidativo em oligoquetas (Eisenia andrei)
(Universidade Federal de Santa Maria, 2023-10-09)
In Brazil, herbicides and fungicides are the most widely used classes of pesticides. Of these
products, the 3 most commercialized are the herbicides Glyphosate (GLY) and 2,4-
Dichlorophenoxyacetic Acid (2,4-D), and the ...
Consequências da exposição ao levonorgestrel em zebrafish: efeitos persistentes e transgeracionais
(Universidade Federal de Santa Maria, 2023-09-18)
The consumption of contraceptive medications such as levonorgestrel (LNG) has
increased considerably in recent decades, and consequently its disposal in the
environment, and it has already been detected in different ...
Avaliação toxicológica de organocalcogênios em eritrócitos humanos
(Universidade Federal de Santa Maria, 2009-07-18)
The interest in organochalcogen chemistry, biochemistry and pharmacology has increased in the last two decades mainly due to the fact that a variety of organochalcogen compounds possess biological activity and due the use ...