Leucemia linfocítica crônica: uma breve revisão

Abstract

The Chronic Lymphocytic Leukemia (CLL) is a disease hematologic neoplasic characterized by the accumulation of monoclonal mature-appearing lymphocytes, normal-appearing, in the blood, bone marrow, lymph nodes, liver, spleen and in other organs; in the large majority of times belong to B-cell phenotype and more unusually to T-cell phenotype. Is the most common form of leukemia in North America and Europe, but is rare in the Orient. The disease occurs in patients with > 60 years age, and is uncommon in individual with less 30 years age and childrens. The ration between men and women is almost 2:1. This work have to finality a revision about CLL, emphasizing initially aspects referring to etiology and pathogeny of disease; evaluating points significants referring to clinical findings, laboratory findings, differential diagnosis and standardize diagnosis; finishing with the evotution and prognostic factors of the patients beyond therapeutics alternatives availables.