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Síntese de 4-(1-fenil-5-trifluormetil-1h-pirazol-4-il)-1h-1,2,3-triazóis promovida por dialquil biaril fosfinas e catálise metálica
(Universidade Federal de Santa Maria, 2017-08-11)
The present dissertation describes the development of a three-step, one-pot methodology, involving the sequential reactions of Sonogashira cross-coupling, deprotection of terminal alkyne (removal of trimethylsilane group), ...
Síntese sequencial linear de 6-((1,2,3-triazol-4-il)metil)-4,5- dimetil-2,6-di-hidro-1h-pirrolo[3,4-d]piridazinonas via reações de N-alquilação, CuAAC e ciclocondensação
(Universidade Federal de Santa Maria, 2017-09-21)
This dissertation presents a synthetic route for obtaining a series of eight 6-((1H-1,2,3-
triazol-4-yl)methyl)-1H-pyrrolo[3,4-d]pyridazin-1-ones with yields of 40-70%. The synthetic
route comprises three distinct steps: ...