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Ação antinociceptiva e anti-inflamatória da fração acetato de etila da casca da Scutia buxifolia Reiss em camundongos
(Universidade Federal de Santa Maria, 2016-02-12)
Pain and inflammation are physiological processes, which when persist can be harmful to health. The pain when improperly or left untreated can become chronic pain. Moreover, the inflammation can be involved in the pathogenesis ...
Desenvolvimento de nanocarreadores a base de piperina: influência do polímero e citotoxicidade in vitro – in vivo
(Universidade Federal de Santa Maria, 2016-12-16)
This study aimed the development of nanoemultions and polymeric nanocapsule suspensions containing
piperine, in order to study their considering photodegradation and citotoxicity. To quantify piperine at the
nanostructures, ...
Avaliação in vitro da atividade de antimicrobianos na cavidade bucal sobre Candida glabrata sensíveis e resistentes ao fluconazol
(Universidade Federal de Santa Maria, 2016-03-21)
Oropharyngeal candidiasis is a challenging fungal disease in the clinical setting of immunocompromised patients, either by their morbidity or by its difficulties in treatment. Patients with AIDS, cancer, and transplanted ...
Desenvolvimento e validação de métodos cromatográficos para avaliação de teor/potência de insulina glargina
(Universidade Federal de Santa Maria, 2016-03-30)
hans, and is secreted into the bloodstream. It plays and important role in regulating the
metabolic activities of the body, particularly the homeostasis of the blood glucose. Insulin
glargine is a recombinant human insulin ...
Validação de métodos cromatográficos para avaliação de estreptoquinase e correlação com o bioensaio
(Universidade Federal de Santa Maria, 2016-03-30)
The streptokinase (STK) is a secreted and isolated molecule of β-hemolytic streptococci,
consists of 414 amino acids and clinically indicated as a thrombolytic agent for myocardial
infarction, deep vein thrombosis, ...
Vitis Vinifera L. cv Pinot Noir: bagaço e borra do vinho como potencial fonte de compostos bioativos
(Universidade Federal de Santa Maria, 2016-07-01)
Food and agricultural industries generate substantial quantities of phenolic-rich by-products
that could be valuable natural sources of antioxidants. The aim of this study was to identify
and quantify the phenolic compounds ...
Caracterização fenotípica e molecular da resistência a clindamicina em isolados clínicos de Staphylococcus aureus de um hospital terciário
(Universidade Federal de Santa Maria, 2016-08-11)
Staphylococcus aureus demonstrated over the time, the ability to develop resistance to the most antimicrobials. The mechanism of resistance to macrolides in S. aureus also reaches lincosamides and streptogramins B, featuring ...
Características genotípicas e fenotípicas de cepas de Escherichia coli isoladas de carne moída bovina in natura
(Universidade Federal de Santa Maria, 2016-01-15)
Escherichia coli is a bacterium that comprise the normal intestinal flora of warm-blooded
animals, responsible for a variety of diseases in humans, as bacteremia, urinary tract and
intestinal infections. Some become ...
Metabolismo de nucleotídeos e nucleosídeo da adenina em linfócitos e plaquetas de pacientes com hepatite C
(Universidade Federal de Santa Maria, 2016-07-19)
Hepatitis C is an infectious disease caused by Hepatitis C virus (HCV) and characterized by development of inflammation as well as fibrosis. On the other hand, the extracellular nucleotides and adenine nucleosides are ...
Avaliação de biomarcadores de estresse oxidativo no diabetes mellitus gestacional
(Universidade Federal de Santa Maria, 2016-07-15)
Gestational diabetes mellitus (GDM) is a glucose intolerance beginning during pregnancy. It is a common disorder and its incidence is increasing among pregnant women. Hyperglycemia derived from GDM is associated with the ...