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Desenvolvimento de nanocápsulas para a liberação controlada de crisina: avaliação da atividade antioxidante e da citotoxicidade in vitro
(Universidade Federal de Santa Maria, 2015-09-25)
Chrysin (5,7-dihydroxyflavone) is a flavonoid (class of flavones), which presents antioxidant and antitumoral activities. However, it has low solubility and hence its bioavailability in the body is low, limiting its ...
Desenvolvimento tecnológico de suspensões e liofilizados de nanocápsulas poliméricas para a veiculação do neuroprotetor idebenona
(Universidade Federal de Santa Maria, 2013-10-30)
Idebenone is an antioxidant, a synthetic derivative of coenzyme Q10, with several applications, such as neuroprotection. However, this drug has low solubility in water, besides is irritant substance and has chemical ...
Desenvolvimento tecnológico de nanocápsulas para a liberação controlada do neuroprotetor vimpocetina
(Universidade Federal de Santa Maria, 2015-05-27)
The Vinpocetine is a synthetic derivative of the vincamine alkaloid, which has a significant neuroprotective effect and is used in the treatment of neurodegenerative diseases such as Alzheimer's and Parkinson's, as well ...
Desenvolvimento de comprimidos de vimpocetina associada a nanocápsulas poliméricas
(Universidade Federal de Santa Maria, 2016-05-20)
Vinpocetine is a derivative of the alkaloid vincamine, widely used for the treatment of cerebrovascular and cognitive disorders due to strong neuroprotective effect. Furthermore, Vinpocetine has also antioxidant, ...