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Validação de método cromatográfico por exclusão molecular para avaliação de interferon-alfa2a e estudos de correlação
(Universidade Federal de Santa Maria, 2010-09-30)
Human interferon-α2a (hIFN-α2a) is a natural protein produced by the cells of the immune system with antiviral, antiproliferative and immunomodulatory properties. A size exclusion liquid chromatography (SE-LC) method was ...
Nanopartículas contendo propionato de clobetasol: preparação, caracterização e incorporação em hidrogéis
(Universidade Federal de Santa Maria, 2010-03-29)
The aim of this work was the development of nanostructured formulations containing
clobetasol propionate. Initially, it was validated a chromatographic method to assay clobetasol
propionate in nanocapsule suspensions. ...
Prospecção in vitro de associações antifúngicas sinérgicas para Fusarium spp
(Universidade Federal de Santa Maria, 2010-03-26)
The genus Fusarium is characterized by hyaline filamentous fungi that cause a wide spectrum of infections predominantly in immunocompromised patients. These fungal infections show high rates of morbidity and mortality and ...
Efeito do tempo de pinçamento do cordão umbilical sobre a anemia fisiológica de recém-nascidos a termo
(Universidade Federal de Santa Maria, 2010-07-14)
This study verified the effect of late clamping (from 1 to 3 minutes after it is
born) of the umbilical cord on the levels of hemoglobin, hematocrite and ferritine in
children at birth, at three months and at six months ...
Desenvolvimento e validação de metodologia para avaliação de fosfato de sitagliptina
(Universidade Federal de Santa Maria, 2010-04-16)
Sitagliptin Phosphate is an oral anti-hyperglycemic belonging to a new class of
medicine used in type 2 diabetes treatment, the dipeptidyl dipetidase -4 (DPP-4) enzyme
inhibitors. This drug besides being safe and tolerated, ...
Avaliação da ligação da albumina humana ao níquel e sua potencial aplicação na detecção da isquemia cardíaca
(Universidade Federal de Santa Maria, 2010-07-16)
Acute coronary syndrome (ACS) is characterized by the occurrence of a set of signs and
symptoms that are related to myocardial ischemia. Unstable angina (UA) and acute
myocardial infarction with ST segment elevation ...