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Tratamento de artrite com vitamina D3 livre ou nanoencapsulada: efeito sobre ectoenzimas de linfócitos em modelo animal
(Universidade Federal de Santa Maria, 2014-04-22)
Rheumatoid arthritis (RA) is a chronic, multisystem inflammatory disease characterized by symmetric and erosive synovitis. The purinergic signaling system plays an important role in the modulation of inflammatory and immune ...
Avaliação das atividades citotóxica e antibacteriana de compostos triazenos
(Universidade Federal de Santa Maria, 2013-12-13)
Neoplasms are a major cause of death worldwide and have been worrying about the medical and scientific community, as most anticancer vector does not act on cancer cells, triggering numerous side-effects and, in some cases, ...
Descrição de isolado clínico de Bordetella trematum por sequenciamento de genoma total
(Universidade Federal de Santa Maria, 2019-07-18)
Bordetella trematum is a Gram-negative coccobacillus found in wounds, diabetic foot ulcers,
otitis, peritonitis and bacteremia. Usually it does not cause infections in humans. There are
few case reports described in the ...
Comparação de metodologias para detecção da resistência à meticilina em Staphylococcus aureus
(Universidade Federal de Santa Maria, 2013-11-29)
Staphylococcus aureus is considered as a microorganism belonging to the normal flora of humans, being both a settler as an infectious pathogen Methicillin-resistant Staphylococcus aureus (MRSA) has emerged as a major cause ...
Perfil de suscetibilidade de isolados de Malassezia pachydermatis, comensais e patógenos, frente a agentes antifúngicos
(Universidade Federal de Santa Maria, 2012-01-30)
Malassezia pachydermatis is opportunistic yeast that primarily affects animals,
being associated with dermatomycoses and ear diseases in dogs and cats. This is
important yeast in veterinary medicine and therefore the ...
Hidrogel de base nanotecnológica contendo silibinina com ação anti-inflamatória no modelo de óleo de cróton
(Universidade Federal de Santa Maria, 2018-11-30)
Currently, irritant contact dermatitis is the most prevalent dermatitis among the others and is triggered
by the activation of innate immunity after skin contact with irritants. Silibinin (SB), a naturally occurring ...
Nanocápsulas de poli(ɛ-caprolactona) contendo vimpocetina: desenvolvimento e avaliação da atividade anticonvulsivante
(Universidade Federal de Santa Maria, 2017-02-13)
Epilepsy is a disease characterized by convulsive seizures, caused by an excessive neuronal electrical discharge, which affects 50 million people worldwide. Vinpocetine, derived from the alkaloid vincamine, is a neuroprotective ...
Ebastina: obtenção de novas formas cristalinas e caracterização no estado sólido
(Universidade Federal de Santa Maria, 2015-12-04)
Ebastine (EBA) is a second-generation antihistamine with poor water solubility. It is used in the treatment of allergic rhinitis and chronic idiopathic urticaria. For oral administration of drugs, there is a preference for ...
Vitis Vinifera L. cv Pinot Noir: bagaço e borra do vinho como potencial fonte de compostos bioativos
(Universidade Federal de Santa Maria, 2016-07-01)
Food and agricultural industries generate substantial quantities of phenolic-rich by-products
that could be valuable natural sources of antioxidants. The aim of this study was to identify
and quantify the phenolic compounds ...
Caracterização fenotípica e molecular da resistência a clindamicina em isolados clínicos de Staphylococcus aureus de um hospital terciário
(Universidade Federal de Santa Maria, 2016-08-11)
Staphylococcus aureus demonstrated over the time, the ability to develop resistance to the most antimicrobials. The mechanism of resistance to macrolides in S. aureus also reaches lincosamides and streptogramins B, featuring ...