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Associação da via inflamatória e apoptótica na patofisiologia do acidente vascular encefálico tardio: relação com a dislipidemia
(Universidade Federal de Santa Maria, 2015-01-22)
Stroke occurs when blood flow to the brain is interrupted by an embolic or thrombotic occlusion of a cerebral artery (ischemic stroke) or by bleeding from a ruptured blood vessel (hemorrhagic stroke). Oxidative stress and ...
Efeito farmacogenético do polimorfismo Ala16Val do gene da MnSOD na resposta de pacientes hipercolesterolêmicos a rosuvastatina
(Universidade Federal de Santa Maria, 2015-02-27)
Rosuvastatin is used as a drug of first choice in treating hypercholesterolemia due to
competitive inhibition of HMG-CoA reductase enzyme which converts HMG-CoA to
mevalonic acid which is the rate-limiting step in ...
Avaliação dos efeitos de um campo magnético pulsado sobre a cicatrização cutânea e biomarcadores oxidativos em ratos wistar
(Universidade Federal de Santa Maria, 2015-08-14)
The surgical postoperative period requires rapid, effective and good-quality wound repair. For a better cicatrization process alternatives have been sought to assist wound repair and improve the appearance of scarred region. ...
Terapia de emissão de luz por diodo induz analgesia em modelos de nocicepção em camundongos: análise do mecanismo de ação
(Universidade Federal de Santa Maria, 2015-09-04)
The LEDT is a fairly recent category of phototherapy and there is evidence that accelerates wound healing, reduce inflammation and painful. However, there are few scientific studies on the action mechanisms of LEDT in pain ...
Investigação da presença e migração de metais presentes em estabilizantes e catalisadores em embalagens plásticas
(Universidade Federal de Santa Maria, 2015-03-16)
The polyvinyl chloride (PVC) and polyethylene terephthalate (PET) polymers are widely used throughout the world. Different types of compounds are used in the polymer synthesis and to improve their properties. In the case ...
Efeito da morfina sobre a persistência da memória de medo condicionado contextual em ratos
(Universidade Federal de Santa Maria, 2015-01-16)
It is established that opioids modulate brain networks involved in learning and memory. Studies using various learning tasks have shown that morphine impairs many forms of memory. A common feature of these studies is that ...
Estudos analíticos para caracterização e avaliação de interleucina-11 humana recombinante
(Universidade Federal de Santa Maria, 2015-12-04)
Interleukin 11 (IL-11) is an endogenous cytokine that directly stimulates the proliferation of hematopoietic stem cells and megakaryocytic progenitor cells and induces megakaryocytic maturation. With advances in biotechnology, ...
Influência dos ácidos graxos da dieta sobre parâmetros de adicção à anfetamina em ratos: aspectos comportamentais, bioquímicos e moleculares
(Universidade Federal de Santa Maria, 2015-07-16)
Polyunsaturated fatty acids (PUFA) are constituents of neuronal membrane
phospholipids which play key roles in the development and functioning of the brain. The last
decades have been accompanied by changes in dietary ...
Avaliação do efeito do suco de uva orgânico como radiomodificador em modelos experimentais de radiobiologia
(Universidade Federal de Santa Maria, 2015-12-17)
The ionizing radiation exposure is able to affect the organic functions. The acute exposure produce several side effects as immunosuppression, gastrointestinal diseases, dermatitis and cardiac damage. Fractionated and ...
Desenvolvimento de nanocápsulas para a liberação controlada de crisina: avaliação da atividade antioxidante e da citotoxicidade in vitro
(Universidade Federal de Santa Maria, 2015-09-25)
Chrysin (5,7-dihydroxyflavone) is a flavonoid (class of flavones), which presents antioxidant and antitumoral activities. However, it has low solubility and hence its bioavailability in the body is low, limiting its ...