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Avaliação de novos compostos sobre a atividade de colinesterases em modelos in silico e in vitro
(Universidade Federal de Santa Maria, 2012-06-04)
The enzyme acetylcholinesterase (EC 3.1.1.7, AChE) is responsible to terminate acetylcholine activity in
the terminal nervous junctions with its effector organs or post-synaptic sites. The activity of this enzyme
could ...
Efeito da quercetina na atividade de ectoenzimas e da acetilcolinesterase em sinaptossomas do córtex cerebral de ratos expostos ao cádmio
(Universidade Federal de Santa Maria, 2012-02-27)
Cadmium (Cd) is one of the most toxic heavy metals by their ability to affect the vital
organs like liver, kidney, brain and other. This metal can trigger a framework of
oxidative stress by increase of reactive oxygen ...
Derivados dos ácidos clorogênico, cafeico e cinâmico: obtenção, avaliação da atividade antimicrobiana e de inibição enzimática
(Universidade Federal de Santa Maria, 2012-04-27)
In recent years there has been an increase in researches for new enzyme inhibitors on
medicinal plants used in the treatment of disorders such as schizophrenia, anxiety, amnesia,
different stages of depression and bipolar ...
Disseleneto de p-metoxi fenila atenua o prejuízo cognitivo e a injúria cerebral em um modelo da doença de Alzheimer em roedores
(Universidade Federal de Santa Maria, 2012-09-17)
Alzheimer s disease (AD) is a progressive neurodegenerative disorder, mainly characterized by memory and intellectual capacity loss. AD is characterized by deposition of amyloid-β peptide, neurofibrillary tangles, ...
Avaliação da atividade de ectonucleotidases e acetilcolinesterase em ratos expostos à fumaça de cigarro e nicotina
(Universidade Federal de Santa Maria, 2012-01-30)
Cigarette smoke is a serious health problem and the most important cause of avoidable death
in the world. It has a complex mixture with more than 4700 constituents, including nicotine and
reactive oxygen species (ROS). ...