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Estudo do comportamento químico de heterociclos trifluormetil substituídos em reações com DAST
(Universidade Federal de Santa Maria, 2011-03-01)
This work describes the study of the chemical behavior of trifluoromethyl substituted heterocycles as 1H-pyrazoles, 2-pyrazolines, 2H-cromenones and isoxazolines in reactions with DAST, with the aim of evaluating possible ...
Reações de 1,1,1-tricloro-4-metoxi-3-penten-2-ona com hidrazinas monosubstituídas
(Universidade Federal de Santa Maria, 2005-02-18)
The 1,1,1-trichloro-4-methoxy-3-penten-2-ona (CCl3COCH=CHOMe) reaction with hydrazines series (RNHNH2, where R = H, Me, tert-Bu, Ph, Ph(F)5, Ph-4-NO2, CO2Me e CONH2) yield to the pyrazoles N-substituted and derivatives ...
Reação de alquinos terminais com 1,1,1-trialo-4-alcóxi-3- alquen-2-onas
(Universidade Federal de Santa Maria, 2005-02-21)
In this work a convenient method of synthesis of 9 eninones is presented, through the reaction of different acetylenes (phenylacetylene, 1-heptyne and 1-hexyne) with n-butillithium and subsequently with electrophiles ...
Síntese e atividades antimicrobiana/antioxidante de 1-(pirazolin-1-il)-2-[(aril/heteroaril)metileno] carboidrazidas trifluormetil substituídas
(Universidade Federal de Santa Maria, 2010-09-16)
This work initially describes the regioselective synthesis of a series of 3-alkyl(aryl/heteroaryl)-5-trifluoromethyl-5-hydroxy-4,5-dihydro-1H-pyrazole-1-carbohydrazides (2) from the monocyclocondensation reaction of ...
Síntese de 2-[3h-pirazol-2-il]trifluormetilpirimidinas Alquil, aril e heteroaril substituidas
(Universidade Federal de Santa Maria, 2004-07-14)
This work describes a general methodology for the synthesis of a novel series of 4-alkyl, 4-aryl, heteroaryl-2-[5-methyl-4-(2-hidroxyethyl)-3-oxo-1,2-dihydro-3H-pyrazol-2-yl]-6(4)-trifluoromethylpyrimidines. The precursors ...
Síntese de 4-(fur-2-il)- e 4-(tien-2-il)-pirimidinas a partir de β-Alcoxivinil trifluormetil cetonas
(Universidade Federal de Santa Maria, 2005-08-01)
The cyclocondensation of the 1,1,1-trifluoro-4-methoxy-4-(2-heteroaryl)-3-buten-2-ones (heteroaryl = furyl and thienyl) with urea and amidines (acetamidine, benzamidine, guanidine, 1H-pyrazole-1-carboxamidine and ...
Reações regioespecíficas de β-alcoxivinil trialometil cetonas com heteroaroilhidrazinas
(Universidade Federal de Santa Maria, 2004-12-20)
This work describe the regiospecific synthesis of three novel series of 1-(2-thenoyl)-, 1-(2-furoyl)- and 1-(isonicotinoyl)-3-alkyl(aryl)[heteroaryl]-5-hydroxy-5-trihalomethyl-4,5-dihydro-1H-pyrazoles, in good yields (50 ...
Obtenção quimiosseletiva de trialometil-β-dicetonas via reações de acilação de acetais
(Universidade Federal de Santa Maria, 2009-02-27)
This work presents an Acylation Method of Acetals applied to the quimioseletive obtention of trifluormethyl-β-diketones, incluing acetals derived from not symmetrical ketones and functionalized substituents. Five known ...
5-trialometil-4,5-diidro-1h-1-(carbonilpiridil)pirazóis: síntese e atividade biológica frente ao Mycobacterium tuberculosis
(Universidade Federal de Santa Maria, 2008-08-06)
This work describes the synthesis of series of 5-hydroxy-3-[alkyl(aryl/heteroaryl)]-5-trifluoro[chloro]methyl-4,5-dihydro-1H-1(carbonylpyridyl)pyrazoles, obtained from the
reactions of 1,1,1-trihalo-4-[alkyl(aryl/hetero ...
Síntese de derivados vinílicos e enínicos de fósforo e aplicação sintética de dissulfetos imidazolidínicos quirais em reações assimétricas
(Universidade Federal de Santa Maria, 2002-07-26)
In this work, we developed a method to prepare β-alkynylvinylphosphonates 3 via a
palladium-catalyzed cross-coupling reaction of β-n-butyltellurovinylphosphonates 2 with
terminal alkynes. The compounds 2 were prepared ...