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A ação anti-inflamatória do lítio é influenciada por fatores genéticos, nutricionais e fármacos antidepressivos: estudos in vitro
(Universidade Federal de Santa Maria, 2017-09-01)
Population aging has increased the prevalence of chronic non-communicable diseases, including psychiatric disorders such as depression and bipolar spectrum disorders (BSDs). Evidence suggests that such disorders are ...
Papel do magnésio na prevenção e reversão de distúrbios motores experimentalmente induzidos
(Universidade Federal de Santa Maria, 2014-10-31)
Chronic treatment of psychotic disorders is associated with adverse effects that affect
motor function. Movement disorders include Parkinsonism, akathisia, dystonia and tardive
dyskinesia. Magnesium (Mg) is an essential ...
Neuroinflamação e via apoptótica na epilepsia
(Universidade Federal de Santa Maria, 2015-02-09)
Epilepsy is a neurological disease that affects around 1% of world population, with neurobiological, neurochemical, cognitive and psychological consequences. Despite the good prognosis, the high number of epilepsy patients ...
Envolvimento de fatores oxidativos e inflamatórios sobre a resistência ao tratamento com fluoxetina em um modelo de depressão em camundongos
(Universidade Federal de Santa Maria, 2021-10-27)
Major depression (DM) is among the most disabling mental disorders in the world. According to the World Health Organization (WHO), more than 300 million people are affected by DM. The disorder is characterized by a set of ...
Efeito do beta-cariofileno na suscetibilidade hepática e renal à aflatoxina B1 em parâmetros bioquímicos, oxidativos e moleculares em ratos
(Universidade Federal de Santa Maria, 2021-08-13)
Aflatoxin B1 (AFB1) is a mycotoxin produced manly by Aspergillus flavus and Aspergillus
parasiticus fungi. Among the existing mycotoxins, AFB1 has been the most studied due to its
high toxigenic potential. Exposure to ...
Alterações bioquímicas e estresse oxidativo associados ao hipotireoidismo
(Universidade Federal de Santa Maria, 2010-03-18)
Overt hypothyroidism is characterized by decreased of thyroid hormones synthesis,
with elevation of thyroid-stimulating hormone (TSH). It s a common disorder in
population with highest prevalence in women and with aging. ...
Efeito da toxicidade do alumínio sobre a resposta antioxidante endógena em três genótipos de aveia
(Universidade Federal de Santa Maria, 2016-08-10)
Aluminum (Al) is a metal that presents toxic effect on plant growth in acidic soils. In these soils, with pH under 5.5, Al can be found in its trivalent form (Al3+), which might compromise the root growth, as well as affect ...
Influência dos diferentes ácidos graxos da dieta sobre um modelo animal de mania induzido por anfetamina em ratos
(Universidade Federal de Santa Maria, 2010-04-22)
Fatty acids (FA) are constituent important of the neuronal phospholipids membranes and they carry out important functions in the development and function of the brain During the last decades changes were observed in the ...
Benznidazol livre e nanoestruturado na terapia da Doença de Chagas experimental e seus efeitos sobre biomarcadores do sistema colinérgico e estresse oxidativo
(Universidade Federal de Santa Maria, 2022-01-27)
Chagas disease (CD) is widely distributed in Latin America, caused by Trypanosoma cruzi. The infection promotes an inflammatory process, which triggers several factors of the immune response. The cholinergic system acts ...
O extrato hidroalcóolico das folhas de Arachis hypogaea L (Fabaceae) produz atividade antioxidante e anti-inflamatória in vitro sem a indução de toxicidade in vitro ou in vivo
(Universidade Federal de Santa Maria, 2020-03-26)
Arachis hypogaea (peanut) leaves are traditionally used for the treatment of insomnia and inflammation. This study aimed to examine the phytochemical composition of peanut leaf hydroalcoholic extract (PLHE) and to describe ...