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Influência da suplementação de diferentes ácidos graxos sobre o fotodano da pele induzido pela exposição de roedores à radiação ultravioleta
(Universidade Federal de Santa Maria, 2014-02-18)
Diet fatty acids (FA) are fundamental to the phospholipids structure and function of cell membranes, in which long chain polyunsaturated FA (PUFA) increase its fluidity, while the trans FA (TFA) to make it more rigid. Also, ...
Influência farmacogenética da enzima SOD2 na resposta in vitro ao resveratrol de células mononucleares
(Universidade Federal de Santa Maria, 2014-10-03)
Resveratrol (RES) is an anti-aging molecule that provides both anti-inflammatory and antioxidant properties. However, it is unclear whether the basal oxidative state of the cell has any influence on the effects of this ...
Efeito cito-genômico do peróxido de hidrogênio e do guaraná (Paullinia cupana) em células tronco mesenquimais
(Universidade Federal de Santa Maria, 2014-01-22)
With advances in techniques of cell culture, stem cells (SCs) have to be used as an alternative therapy, firming the called regenerative medicine. An type of SC that has been studied is the Adipose-derived stem cell (ASCs) ...
Efeito da administração oral de aflatoxina B1 nas convulsões induzidas em ratos
(Universidade Federal de Santa Maria, 2014-08-14)
Aflatoxins are produced by Aspergillus flavus fungi, mainly A. parasiticus and A. nomius. Aflatoxin B1 (AFB1) is the most common and highly toxic mycotoxin, presents carcinogenic, mutagenic and teratogenic effects. This ...
Efeito in vitro da suplementação do guaraná (Paullinia cupana) na atividade de quimioterápicos usados no tratamento do câncer de mama
(Universidade Federal de Santa Maria, 2014-01-24)
Cancer related fatigue (CRF) is a common phenomenon in patients undergoing chemotherapy and radiotherapy representing a negative impact on functional status and quality of life. Some plants present tonic and antifatiguing ...
Efeito farmacogenético e farmacogenômico do metotrexato na citotoxicidade de células mononucleares periféricas do sangue
(Universidade Federal de Santa Maria, 2014-07-18)
Methotrexate (MTX) is an antimetabolite drug analogue of folic acid with wide clinical application, used in high doses for the treatment of cancer and in low doses for the treatment of autoimmune diseases such as rheumatoid ...
Efeito de dose única de vitamina D nas concentrações séricas de citocinas em mulheres idosas na pós-menopausa
(Universidade Federal de Santa Maria, 2014-03-07)
Vitamin D is an important immunomodulator. Epidemiological studies have shown that vitamin D deficiency impairs the immune functions and participates in the pathogenesis of infectious and autoimmune diseases. Vitamin D ...
Efeito da dieta enriquecida com rutina sobre os parâmetros sanguíneos e biomarcadores oxidativos em jundiás (Rhamdia quelen)
(Universidade Federal de Santa Maria, 2014-08-14)
Silver catfish, Rhamdia quelen, is one of the most cultivated fish species in southern Brazil. Products destined for improving rearing and production of this species are required due to its importance for aquaculture. ...
Efeito da exposição aguda à fumonisina B1 nas convulsões induzidas por pentilenotetrazol em camundongos
(Universidade Federal de Santa Maria, 2014-07-24)
Mycotoxins are secondary metabolites, produced by fungi species of the genus Aspergillus,
Fusarium, Penicillium and Claviceps. The high incidence of toxicity is by ingestion of
contaminated plant products and by consuming ...
Eficácia da escada analgésica da organização mundial da saúde (OMS) em um modelo de síndrome dolorosa induzida por paclitaxel em ratos
(Universidade Federal de Santa Maria, 2014-04-09)
Paclitaxel use in cancer is limited by a painful syndrome characterized by acute and chronic phases and by the lack of efficacious therapies. Thus, we assessed the efficacy of analgesics used in the World Health Organization ...