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Efeito dos organocalcogênios sobre a atividade da enzima δ-ALA-D sanguínea: estudos in vitro e em humanos expostos ocupacionalmente a estes compostos
(Universidade Federal de Santa Maria, 2002-10-03)
Organochalcogens are important intermediates and the main applied reagents
in organic synthesis, which can increase human exposure risk to these
chemicals in the workplace. Since, the erythrocytic δ-ALA-D activity could
be ...
Efeito das poliaminas sobre a lipoperoxidação induzida por neurotoxinas em encéfalo de ratos
(Universidade Federal de Santa Maria, 2004-01-16)
Polyamines, among other functions, are considered to act as a free radical
scavenger and antioxidant. The quinolinic acid, sodium nitroprusside and iron
stimulate production of free radicals and consequent lipid peroxidation, ...
Avaliação dos efeitos do citrato de sódio sobre o metabolismo lipídico e da acetilcolina em camundongos
(Universidade Federal de Santa Maria, 2002-07-30)
The sodium citrate is one of the most utilized in chemical food additives that have
been found in tinned and milk derivatives. Its proprieties are: stabilizer, emulsifier and
acidity regulator. The chemical compound can ...
Administração sistêmica de agentes poliaminérgicos modula a memória na tarefa de medo condicionado em ratos
(Universidade Federal de Santa Maria, 2006-12-01)
The polyamines, spermine, spermidine and putrescine, are a group of aliphatic amines that interact with diverse cellular targets such as nucleic acids and proteins. The polyamines may act as physiological modulators of ...
Efeito hiperalgésico produzido pela administração de bradicinina na amígdala de ratos
(Universidade Federal de Santa Maria, 2006-08-31)
The peptide bradykinin is one of the most potent algogenic substances and its role in nociception has been intensively studied in the peripheral nervous system. However,
its action in pain transmission in central nervous ...
Avaliação do potencial antinociceptivo de novos 3-Metil-1H-1-pirazol metil esteres 5-substituídos em Camundongos
(Universidade Federal de Santa Maria, 2007-08-31)
In the present study the antinociceptive activity of six 1-H-1-pyrazol methyl ester derivatives in the hot-plate test and Complete Freund s Adjuvant (CFA)-induced inflammation in mice was investigated. The administration ...