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Caracterização físico-química do mel do bioma pampa brasileiro e estudo do seu potencial antioxidante in vitro e in vivo em modelo de Drosophila melanogaster
(Universidade Federal de Santa Maria, 2014-03-14)
Honey is a complex mixture produced by honey bees from the nectar, which is used by
its sweetening properties, as well as by its human health benefits. The aim of this study was to
characterize, for the first time in ...
Centella asiática reduz peroxidação lipídica induzida por ácido quinolínico e nitroprussiato de sódio in vitro em regiões do cérebro de rato
(Universidade Federal de Santa Maria, 2014-08-21)
The oxidative stress is envolved in several diseases, including neurological diseases. Centella asiatica is a medicinal plant which was has long been used to treat neurological disturbances in Ayurvedic medicine. The aim ...
Avaliação dos efeitos de drogas anti-adenosinérgicas e do disseleneto de difenila no prejuízo da memória e estresse oxidativo relacionados ao envelhecimento
(Universidade Federal de Santa Maria, 2012-08-08)
Biological aging is gradual and progressive decline of physical functions that begin in adulthood and ends with death in almost all animals species. One of the most common features of aging is the reduced ability to learn ...
Efeitos do tratamento com ácido gálico sobre parâmetros oxidativos, moleculares e comportamentais induzidos por cetamina em ratos
(Universidade Federal de Santa Maria, 2019-12-20)
Ketamine is a dissociative anesthetic drug, which blocks NMDA glutamatergic receptors for restricted clinical use due to its high addictive potential. Studies have shown neurotoxicity and memory impairments development ...
Estudo fitoquímico e de toxicidade (aguda e subaguda) de Celtis iguanaea (Jacq.) Sarg. em ratos Wistar
(Universidade Federal de Santa Maria, 2015-03-27)
The Celtis iguanaea species is popularly known as esporão-de-galo and its leaves are used in folk medicine to treat body aches, rheumatism, asthma, colic, indigestion, ulcers, and as a diuretic, and roots for urinary ...
Depressão: aspectos fisiopatológicos e o efeito tipo-antidepressivo da apocinina
(Universidade Federal de Santa Maria, 2020-02-17)
Depression is considered a public health challenge around the world. According to the World Health Organization, more than 300 million people (approximately 6% of the world population) are affected by this disorder. ...
Avaliação de marcadores bioquímicos, de estresse oxidativo e do efeito antioxidante da quercetina no hipotireoidismo
(Universidade Federal de Santa Maria, 2014-03-28)
Hypothyroidism is characterized by a disorder resulting from deficiency of
thyroid hormones and is related to lipid metabolism dysfunction and cardiovascular
diseases development risk. However, these changes in hypothyroidism ...
Efeitos dos compostos de selênio e zinco nas lesões gastrointestinais induzidas por etanol em ratos
(Universidade Federal de Santa Maria, 2012-03-30)
Gastric ulcer is a world widespread illness that affectes a great number of people and it is correlated to life style, food intake, alcohol and smoke in association or not to stress behavior. The lesions are in association ...
Disseleneto de p-metoxi fenila atenua o prejuízo cognitivo e a injúria cerebral em um modelo da doença de Alzheimer em roedores
(Universidade Federal de Santa Maria, 2012-09-17)
Alzheimer s disease (AD) is a progressive neurodegenerative disorder, mainly characterized by memory and intellectual capacity loss. AD is characterized by deposition of amyloid-β peptide, neurofibrillary tangles, ...
Avaliação da atividade antioxidante de diferentes classes de compostos contra a oxidação de lipoproteínas de baixa densidade
(Universidade Federal de Santa Maria, 2011-10-04)
Abnormalities of lipid metabolism often lead to pathologic lipid accumulation in the
vessel wall, oxidative and chronic inflammatory sequelae and the formation of atherosclerotic
lesions, ultimately leading to clinical ...