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Efeito do tipo antidepressivo do 7-flúor-1,3-difenilisoquinolina-1-amina em modelos de estresse em roedores
(Universidade Federal de Santa Maria, 2018-03-23)
Current treatments for depression are inadequate for many patients and progress in understanding of this psychiatric disease is slow. The isoquinoline is an important class of molecules with antidepressant-like effect in ...
Respostas bioquímicas em carpas (Cyprinus carpio) expostas ao fungicida tebuconazole (folicur® 200 ec)
(Universidade Federal de Santa Maria, 2010-07-22)
The intensive use and/or inadequate management of pesticides have led to contamination of the aquatic ecosystem, reaching the biota living there, including the fish. Pesticides can affect toxicological parameters these ...
Avaliação dos efeitos biológicos do (s) (3-feniltelanil propanamida) succinato de dimetila, um novo telúrio aminoácido derivado do ácido aspártico
(Universidade Federal de Santa Maria, 2011-03-25)
Recent studies from our group demonstrated that the (S)-dimethyl 2-(3-(phenyltellanyl) propanamido) succinate compound, a telluroamino acid showed glutathione peroxidase (GPx)-like activity, attesting to its antioxidant ...
Efeito da exposição in vivo ao ditelureto de difenila em camundongos: evidências para estresse oxidativo
(Universidade Federal de Santa Maria, 2010-09-24)
In this work, we investigated the effect of (PhTe)2 administration (10 μmol/kg and 50 μmol/kg) to adult mice on the behavioral performance and on some parameters of oxidative stress in the brain ad liver. The animals ...
Ratas lactantes e não lactantes diferem quanto à sensibilidade ao HgCl2: efeito protetor do ZnCl2
(Universidade Federal de Santa Maria, 2012-08-17)
Mercury is a divalent metal found in the liquid state at room temperature without biological function. Occupational exposure to this metal occurs mainly in industrial activities and agriculture. Its toxicity seems to be ...
Efeitos do exercício resistido sobre componentes do sistema purinérgico e parâmetros de estresse oxidativo em modelo experimental de sepse
(Universidade Federal de Santa Maria, 2018-09-28)
Sepsis is a generalized infection that causes changes in the purinergic and immune systems, the inflammatory parameters and the oxidative status of the patients. Physical exercise, through its anti-inflammatory and antioxidant ...
Análise de biomarcadores em jundiás (Rhamdia quelen) expostos in situ como uma ferramenta de avaliação ambiental
(Universidade Federal de Santa Maria, 2017-03-24)
Aquatic ecosystems are affected by the use of agrochemicals in agricultural areas near rivers. To evaluate possible impacts, studies with animals that inhabit these ecosystems are needed. In situ exposure is one way of ...
Efeito protetor do exercício físico nas alterações bioquímicas e cognitivas iniciais e tardias induzidas pelo traumatismo cranioencefálico em ratos
(Universidade Federal de Santa Maria, 2014-08-23)
Traumatic brain injury (TBI) is a major cause of morbidity and mortality in industrialized countries leading to the motor and cognitive deficits. Evidence demonstrated that exercise is neuroprotective in traumatic brain ...
Efeito do exercício agudo de curta duração na atividade da enzima δ-aminolevulinato desidratase em humanos
(Universidade Federal de Santa Maria, 2009-02-27)
Aerobic exercise of sufficient intensity and duration can result in increased generation of reactive oxygen species and exercise of extreme endurance may cause oxidative stress with a concomitant decreased activity of ...
Efeitos da Campomanesia xanthocarpa em parâmetros bioquímicos, hematológicos e de estresse oxidativo em pacientes hipercolestrolêmicos
(Universidade Federal de Santa Maria, 2009-11-16)
In Southern Brazil, the plant Campomanesia xanthocarpa Berg. (Myrtaceae), popularly known as guavirova , has been empirically used for its potential effect in reducing blood cholesterol levels. Since there are no scientific ...