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Papel das poliaminas periféricas no desenvolvimento da dor inflamatória em ratos
(Universidade Federal de Santa Maria, 2010-07-21)
Polyamines (putrescine, spermidine and spermine) are aliphatic amines produced by the action of ornithine descarboxylase (ODC), a rate-limiting and protein kinease C
(PKC)-regulated step in polyamine synthesis. Since the ...
Efeito in vitro do haloperidol e risperidona na ativação inflamatória de macrófagos RAW 264.7
(Universidade Federal de Santa Maria, 2015-04-10)
Introduction: Antipsychotic drugs, such as haloperidol (typical) and risperidone (atypical)
increase the risk of obesity and other endocrine disturbs in psychiatric patients when used in
long term treatments. There is ...
Avaliação da atividade das colinesterases, adenosina desaminase e biomarcadores de inflamação em pacientes com esclerose múltipla
(Universidade Federal de Santa Maria, 2013-08-19)
Multiple sclerosis (MS) is an autoimmune disease complex,
since several pathophysiological
processes, including inf lammation, demyelination, axonal damage and repair mechanisms
are involved in its eme rgence. It attacks ...
Dexmedetomidina diminui a resposta inflamatória após cirurgia miocárdica sob mini-circulação extracorpórea
(Universidade Federal de Santa Maria, 2013-03-09)
Despite great technological advances in coronary artery bypass grafting (CABG) surgery, there is a high incidence of cardiac dysfunction and neurocognitive deficits in the postoperative period. Preventive measures are ...
Papel do receptor TRPV1 em um modelo articular de gota aguda em ratos
(Universidade Federal de Santa Maria, 2014-02-17)
The gout is an extremely painful type of arthritis. Despite the large number of drugs available for its treatment, they usually cause many adverse effects that limit their use. Then, further investigations are necessary ...
Efeitos do exercício físico sobre o processo inflamatório e sobre o déficit motor induzidos pelo traumatismo cranioencefálico em ratos
(Universidade Federal de Santa Maria, 2013-02-21)
Traumatic brain injury (TBI) is a public health problem, and is considered a leading cause of death among children and young adults in industrialized countries. TBI can be defined as a mechanical external aggression to the ...
Avaliação dos sistemas purinérgico e colinérgico no processo inflamatório de pacientes com síndrome metabólica
(Universidade Federal de Santa Maria, 2012-08-28)
Metabolic syndrome (MetS) is characterized by the presence of set cardiovascular risk factors such as hypertension, hyperglycemia, dyslipidemia and abdominal obesity. This pathology has been widely discussed due to the ...
Envolvimento das poliaminas no ataque agudo de gota em camundongos
(Universidade Federal de Santa Maria, 2016-02-26)
Gout attack is characterized severe joint pain and inflammation with concomitant accumulation of monosodium urate (MSU) crystals. However, gout and the mechanisms responsible for the acute attacks are poorly understood, ...