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Estudo químico e biológico de Conyza bonariensis (L.) Cronquist (Asteraceae)
(Universidade Federal de Santa Maria, 2006-06-09)
Conyza bonariensis (L.) is a native plant of South America, easily found in the south area. It s popular name is buva or margaridinha-do-campo. This plant is very used in folk medicine for rheumatism, gout, cystitis, ...
Efeito do extrato de Uncaria tomentosa (Wild.) D.C. na hidrólise de nucleotídeos de adenina em linfócitos de ratos submetidos a modelo experimental de artrite reumatóide
(Universidade Federal de Santa Maria, 2012-07-18)
The extracts of stem and root of the Uncaria tomentosa plant present several properties. Among them, the anti-inflammatory property is very important since it has been studied and widely observed in cases of rheumatoid ...
Desonida: validação de métodos analíticos e estudo de fotoestabilidade de formulações
(Universidade Federal de Santa Maria, 2013-04-26)
Desonide is a nonfluorinated corticosteroid with glucorticoid activity. It is used
topically in the treatment of atopic dermatitis, inflammation, pruritus and seborrheic
dermatitis of mild to moderate severity. In Brazil, ...
Composição fitoquímica e atividade biológica do extrato bruto e frações da Equisetum hyemale
(Universidade Federal de Santa Maria, 2015-11-27)
The use of plants for medicinal purposes is an ancient practice because vegetables have in its composition chemical structures with important pharmacological activities. In this study we highlight the hyemale Equisetum ...
Avaliação da atividade urinária das enzimas gama-glutamiltransferase e fosfatase alcalina para a detecção da nefropatia em pacientes com diabetes Mellitus tipo 2
(Universidade Federal de Santa Maria, 2011-06-17)
Background: Diabetic nephropathy (DN) is defined as a rise in urinary albumin excretion rate, often associated with an increase in blood pressure. It is the leading cause of end-stage renal disease and carries an increased ...
Perfil oxidativo e atividade da enzima delta-aminolevulinato desidratase em gestantes saudáveis e em gestantes com pré-eclâmpsia
(Universidade Federal de Santa Maria, 2016-09-05)
During pregnancy, even being a physiological process, there is an increase in oxidative stress due to increased metabolic demands and increased oxygen consumption in the tissues, especially in the placenta, in response to ...
Controle de qualidade e atividade antimicrobiana de Verbena litoralis Kunth
(Universidade Federal de Santa Maria, 2013-07-31)
Verbena litoralis Kunth belongs to the family Verbenaceae is native to South America and can be found in tropical and subtropical regions, mainly in temperate regions of the southern hemisphere and some temperate regions ...
Validação de bioensaio por cultura de células para avaliação de potência de rhEPO e correlação com bioensaio in vivo e métodos cromatográficos
(Universidade Federal de Santa Maria, 2014-08-12)
Erythropoietin is a hematopoietic hormone and the main physiological function is the induction of erythropoiesis. Recombinant DNA technology enabled cloning and expression of rhEPO gene to produce recombinant human ...
Avaliação dos níveis de albumina modificada pela isquemia, um novo biomarcador de estresse oxidativo, em pacientes com artrite reumatoide
(Universidade Federal de Santa Maria, 2013-01-15)
Rheumatoid arthritis (RA) is a chronic inflammatory, autoimmune disease, characterized by peripheral and symmetrical polyarthritis that leads to joint destruction and deformity due to erosion of cartilage and bone. This ...
Desenvolvimento e validação de metodologia para análise de besilato de anlodipino em formas farmacêuticas
(Universidade Federal de Santa Maria, 2005-04-25)
In this work the quantitative methodologies for determination of amlodipine besilate in tablets and capsules were validated. The methods used for drug determination were: liquid chromatography (LC) and ultraviolet ...