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Efeitos do mercúrio sobre a atividade das enzimas alanina aminotransferase, lactato desidrogenase e glicose 6-fosfatase de ratos jovens
(Universidade Federal de Santa Maria, 2010-03-25)
Mercury is an environmental contaminant, and may accumulate in living organisms causing several damage. Studies have shown that this metal causes several physiological and biochemical alterations in young rats which are ...
Agentes poliaminérgicos modulam a extinção do medo condicionado contextual em ratos
(Universidade Federal de Santa Maria, 2009-11-23)
Polyamines, such as spermidine and spermine, have been reported to improve memory retention through the activation of N-methyl-D-aspartate receptors (NMDAr).
However whether polyamine agonists and antagonists alter extinction ...
Sobre a excitotoxicidade induzida por glutamato em retina embrionária de pinto
(Universidade Federal de Santa Maria, 2004-08-20)
Excitotoxicity refers to the neurodegenerative process initiated by excessive activation of receptors for the neurotransmitter glutamate. This process is one of the
most extensively studied processes of neuronal cell death, ...
Efeitos do herbicida clomazone sobre parâmetros metabólicos e antioxidantes em jundiá (Rhamdia quelen)
(Universidade Federal de Santa Maria, 2004-09-10)
The objective of this study was to evaluate the effect of clomazone herbicide on metabolism of silver catfish (Rhamdia quelen). It was measured levels of lactate, protein and glucose (plasma), glycogen, protein and lactate ...
Sensibilidade da enzima acetilcolinesterase (e.c. 3.1.1.7) à nicotina in vitro e in vivo
(Universidade Federal de Santa Maria, 2005-08-18)
This work valued the sensibility of the acetylcholinesterase from different sources and brain regions at nicotine in vitro, and the effects of the acute and subchronic exposures at the alkaloid on the brain acetylcholinesterase ...
A inibição da enzima δ-aminolevulinato desidratase por monossacarídeos não é mediada pela oxidação de grupos -sh
(Universidade Federal de Santa Maria, 2004-08-18)
Heme pathway enzyme δ-aminolevulinate dehydratase (δ-ALA-D) is a good marker for oxidative stress and metal intoxication. This sulfhydrylic enzyme is inhibited in several oxidative pathologies like lead, mercury and aluminum ...
Quantificação da glutationa reduzida em eritrócitos humanos por cromatografia líquida de alta eficiência-uv: validação e aplicação
(Universidade Federal de Santa Maria, 2005-02-21)
Oxidative stress may be initiated by a decline in the antioxidant defence system or by an overproduction of free radicals leading to an imbalance between oxidants and antioxidants. The most significant alteration in the ...
Derivados pirazolínicos inéditos causam antinocicepção em camundongos no teste da formalina
(Universidade Federal de Santa Maria, 2004-07-29)
The discovery of pyrazole derivatives dates back to 1884, when the German chemist Ludwig Knorr attempted to synthesize quinoline derivatives with antipyretic activity and accidentally obtained antipyrine, a pyrazolinone, ...
Efeito teratogênico do ditelureto de difenila, administrado durante a gestação em ratas e efeito de organocalcogênios sobre a reprodução em ratos machos
(Universidade Federal de Santa Maria, 2004-07-30)
Organochalcogens are important intermediates and the main applied reagents in organic synthesis and in industrial processes, which can increase human exposure risk to these chemicals in the workplace. The effects of single ...
Ratas lactantes e não lactantes diferem quanto à sensibilidade ao HgCl2: efeito protetor do ZnCl2
(Universidade Federal de Santa Maria, 2012-08-17)
Mercury is a divalent metal found in the liquid state at room temperature without biological function. Occupational exposure to this metal occurs mainly in industrial activities and agriculture. Its toxicity seems to be ...