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Itens para a visualização no momento 31-40 of 135
Associação do polimorfismo MnSOD ALA16VAL com os biomarcadores inflamatórios, apoptóticos e BDNF em pacientes após acidente vascular encefálico tardio
(Universidade Federal de Santa Maria, 2017-07-01)
Stroke is one of the most frequent neurologic diseases and involves various risk factors such as atherosclerosis, dyslipidemia and diabetes mellitus. Furthermore, the mechanisms of action associated with the pathophysiology ...
Estudo do potencial antioxidante da espécie Caryocar coriaceum Wittm. em modelos experimentais in vitro e in vivo
(Universidade Federal de Santa Maria, 2016-04-29)
Despite the diversity of species found in the National Araripe Forest, Ceará Cariri, there are few studies with Caryocar coriaceumWittm (C. coriaceum), a plant that produces a highly consumed fruit in regional cuisine. The ...
Influência do manuseio neonatal sobre parâmetros comportamentais, bioquímicos e moleculares após o uso de drogas psicoestimulantes em ratos
(Universidade Federal de Santa Maria, 2016-09-21)
The abusive use of psychostimulant drugs is a common social problem in countries of different cultures, with increasing and alarming incidence, whose discontinuance of use is associated with anxiety and depression cases. ...
Disseleneto de difenila em modelos de infecção viral causada por herpes simplex vírus dos tipos 1 e 2
(Universidade Federal de Santa Maria, 2017-03-02)
Infectious diseases caused by herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) are among the pathologies that most affect the population. The search for new therapeutic alternatives for its treatment becomes relevant ...
Óleos essenciais de Myrcia sylvatica (G. Mey.) DC. e Curcuma longa L. como anestésicos para peixes: efeitos sobre as respostas fisiológicas
(Universidade Federal de Santa Maria, 2016-12-16)
The use of anesthetic substances is necessary to reduce stress and provide fish welfare during aquaculture
practices. The aim of this study was to investigate the use of Myrcia sylvativa (EOMS) and Curcuma longa
(EOCL) ...
Avaliação do dano ao DNA em pacientes com doença renal crônica submetidos à hemodiálise e sua associação com o metabolismo do ferro e estresse oxidativo
(Universidade Federal de Santa Maria, 2016-06-14)
Chronic kidney disease (CKD) is a condition in which the kidneys lose their ability to perform basic functions. Hemodialysis is the most commonly used alternative treatment for these patients, however, it exposes these ...
Efeito do desbalanço genético e farmacológico do metabolismo oxidativo em indicadores de fertilidade masculina
(Universidade Federal de Santa Maria, 2016-12-07)
Previous studies indicate that changes in oxidative metabolism may play a role in reproductive
success. Manganese-dependent superoxide dismutase enzyme (SOD2), a key in the oxidative
balance, presents a genetic variation ...
Caenorhabditis elegans como modelo experimental para estudos toxicológicos e farmacológicos dos extratos de Luehea divaricata e Paullinia cupana
(Universidade Federal de Santa Maria, 2016-03-16)
The nematode Caenorhabditis elegans is a valuable tool for toxicological and
pharmacological studies. Despite its simple body, the most part of its genes and signaling
pathways are similar to humans, and alterations in ...
Envolvimento dos sistemas purinérgico, colinérgico e estresse oxidativo nos distúrbios da tireoide: possível efeito protetor da quercetina
(Universidade Federal de Santa Maria, 2017-02-22)
Thyroid hormones modulate the metabolic pathways in the body and have important physiological
functions in the brain and vascular system. Changes in their production or distribution lead to disorders
such as hypothyroidism ...
Influência de Harpagophytum procumbens sobre parâmetros comportamentais e moleculares em um modelo de discinesia orofacial em ratos
(Universidade Federal de Santa Maria, 2017-02-18)
Fluphenazine is a typical antipsychotic used for the treatment of schizophrenia. However, its chronic use has been related to the appearance of extrapyramidal side effects, such as tardive dyskinesia (TD). Studies suggest ...