Perfil de resistência aos antimicrobianos de Staphylococcus coagulase positiva isolados de cães, gatos e humanos: meta-análise

Abstract

Among the approaches of ―One Health‖, the use of antimicrobials in humans, animals and food production has been discussed. Antimicrobial resistance is a public health problem, where many microorganisms have become progressively resistant to antimicrobials. In veterinary medicine, resistance of pathogens to antimicrobials has also been a frequent and worrying finding. This is mainly due to the indiscriminate use of antimicrobials. The proximity between dogs, cats and humans is increasing, since the animals are considered members of the family and live inside the residences. Both animals and humans can serve as reservoirs of multiresistant bacteria. Possibly this factor is responsible for the dissemination of resistance genes between bacteria, mainly of the genus Staphylococcus, between dogs, cats and humans. The aim of this research is to perform a meta-analytical study regarding the resistance profile found in dogs, cats and humans. A retrospective study of publications was carried out over 20 years. Our hypothesis is that companion animals can disseminate resistance genes in the environment where they live, becoming a significant source of recolonization in the urban context. Through the results obtained, it was possible to evaluate the resistance profile of coagulase-positive Staphylococcus against antimicrobials among the target species, correlating our results with daily actions and prudent measures of use of the antibiotics.