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Influência da estimulação tátil neonatal associada à administração de antidepressivo, sobre parâmetros comportamentais e bioquímicos em ratos jovens
(Universidade Federal de Santa Maria, 2017-02-10)
Early life events, in both humans and animals, may influence on brain development, leading to long-term consequences on adult behavior. Thus, this study was carried out in order to assess the influence of neonatal tactile ...
Efeito protetor do extrato de lingonberry sobre o sistema purinérgico e estresse oxidativos no sistema nervoso de ratos diabéticos
(Universidade Federal de Santa Maria, 2015-10-23)
Diabetes mellitus (DM) is considered a metabolic disorder that affects large part of worldwide. The hyperglycemia of diabetes cause cognitive impairments associated with physiological and structural changes in the central ...
Avaliação da atividade de enzimas que hidrolisam nucleotídeos e nucleosídeo de adenina em pacientes com melanoma cutâneo.
(Universidade Federal de Santa Maria, 2015-08-20)
The Cutaneous Melanoma (CM) is considered responsible for most deaths related to skin cancer. The frequency of new cases and incidence is increasing, especially among young people. In Brazil the highest rates are in the ...
Artemísia absinthium minimiza a toxicidade induzida por paracetamol em camundongos
(Universidade Federal de Santa Maria, 2015-09-22)
Acetaminophen is a popular analgesic associated with toxic ingestions. There are many studies about prevention of APAP induced hepatotoxicity including the medicinal plants. Artemisia absinthium (AA) is one of them, but ...
Efeito hipolipidêmico e hepatoprotetor do 4,4’-dicloro-difenil disseleneto em um modelo de hiperlipidemia em ratos
(Universidade Federal de Santa Maria, 2016-02-29)
Hyperlipidemia can be manifested by elevation in total cholesterol (TC), triglycerides (TGs) and low density lipoprotein (LDL), as well as by reduction in high density lipoprotein (HDL) levels. Hyperlipidemia is associated ...
Efeitos do ácido gálico em parâmetros bioquímicos e de estresse oxidativo em ratos submetidos a um modelo experimental de diabetes
(Universidade Federal de Santa Maria, 2015-09-11)
Diabetes mellitus (DM) is a metabolic disorder characterized by hyperglycemia associated with the increase of free radicals and decrease in the antioxidant response. Gallic acid has many biological properties, among them ...
Mecanismos envolvidos na proteção do disseleneto de difenila sobre a toxicidade induzida por metilmercúrio em Saccharomyces cerevisiae
(Universidade Federal de Santa Maria, 2015-12-14)
Humans are usually exposed to organic form of mercury, the organometallic cation methylmercury ([CH3Hg]+, MeHg), by eating fish and seafood. The neurotoxic effects of MeHg are already widely known. Individuals exposed to ...
Avaliação dos mecanismos de toxicidade do disseleneto de difenila (PhSe)2 e cloreto de fenilselênio zinco (PhSeZnCl) em Saccharomyces cerevisiae
(Universidade Federal de Santa Maria, 2015-08-21)
Selenium (Se) is a microelement present in different animal tissues in the form of selenoproteins, for example, the glutathione peroxidase (GPx). Organic selenium compounds, such as diphenyl diselenide (PhSe)2 and fenilselenium ...
Efeitos do disseleneto de difenila em carpas expostas a uma formulação comercial contendo cipermetrina e clorpirifós
(Universidade Federal de Santa Maria, 2016-03-11)
Agricultural activity is one of the main factors that lead to the increase of contaminants in aquatic ecosystems and may cause oxidative stress in fish. The objective of this work was to verify the protective effects of ...
Exposição crônica ao herbicida paraquat promove desequilíbrio no sistema antioxidante e alterações comportamentais em peixe zebra (Danio rerio)
(Universidade Federal de Santa Maria, 2015-08-20)
In the last decade, it has been investigated behavioral patterns that may to reflect the physiological and biochemical changes in promising experimental models. Zebrafish (Danio rerio) is an useful tool for studying ...