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Estudo dos efeitos induzidos por doses subletais do inseticida agrícola Tiametoxam sobre parâmetros bioquímicos e comportamentais de baratas da espécie Nauphoeta cinerea
(Universidade Federal de Santa Maria, 2023-09-29)
Thiamethoxam (TMX) is an agricultural insecticide belonging to the neonicotinoid
family. Its mechanism of action lies in the persistent activation of nicotinic acetylcholine
receptors (nAChR) in the nervous system of ...
Efeitos do resveratrol na sinalização purinérgica em camundongos expostos ao alumínio
(Universidade Federal de Santa Maria, 2023-09-12)
Aluminum (Al) is a compound found in nature, and is widely used industrially, which means that humans are exposed to it daily. Due to its ability to cross the blood-brain barrier, it can accumulate in the brain in regions ...
Efeito do exercício físico sobre o desenvolvimento de crises convulsivas pós-traumáticas em ratos: o papel da trombina
(Universidade Federal de Santa Maria, 2023-09-29)
Traumatic brain injury (TBI) affects about 69 million people worldwide and is the major cause
of post-traumatic epilepsy (PTE), a structural acquired type of epilepsy where acute seizures
onset can influence the ...
Caracterização do potencial genotóxico de porfirinas de base livre e metaloporfirinas de Zn (II)
(Universidade Federal de Santa Maria, 2023-09-06)
Photodynamic therapy (PDT) is a treatment with several benefits, such as few side
effects, ease of application and possible combination with other treatments. It is based on the
production of reactive oxygen species (ROS) ...
Avaliação fármaco-toxicológica da molécula JM-20 em Caenorhabditis elegans
(Universidade Federal de Santa Maria, 2023-10-17)
With the discovery of new molecules with pharmaceutical potential, studies examining different mechanisms of action and toxicological aspects emerge. The 3-ethoxycarbonyl-2-methyl-4-(2-nitrophenyl)-4,11-dihydro-1H-pyrido ...
Curva dose-resposta do extrato lipofílico composto por clorofilas e carotenoides da microalga Scenedesmus obliquus: papel oxidativo e envolvimento da sinalização purinérgica
(Universidade Federal de Santa Maria, 2023-09-27)
More and more innovative proposals based on bioactive compounds are being presented to
the public. The use of microalgae, such as the species Scenedesmus obliquus, has played
an interesting role in this regard through ...
Avaliação da toxicidade de pesticidas sobre o crescimento e biomarcadores de estresse oxidativo em oligoquetas (Eisenia andrei)
(Universidade Federal de Santa Maria, 2023-10-09)
In Brazil, herbicides and fungicides are the most widely used classes of pesticides. Of these
products, the 3 most commercialized are the herbicides Glyphosate (GLY) and 2,4-
Dichlorophenoxyacetic Acid (2,4-D), and the ...
O efeito de concussões recorrentes no comportamento neuropsiquiatrico em camundongos submetidos a um protocolo de exercício físico de alta intensidade
(Universidade Federal de Santa Maria, 2023-11-08)
Traumatic brain injury (TBI) affects millions of people worldwide, being one of the main causes of disability and death, with mild trauma or concussion making up more than 50% of TBI cases. Concussion is a common event in ...
Síntese e atividade anti-pythium insidiosum in vitro de três novos compostos triazólicos
(Universidade Federal de Santa Maria, 2023-11-08)
Pythiosis is an infectious and non-transmissible disease caused by the oomycete Pythium
insidiosum, which mainly affects horses, dogs and humans. Currently, there is no effective drug
treatment. Triazoles are heterocyclic ...