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Itens para a visualização no momento 21-30 of 71
Efeito da (+)-catequina sobre adiscinesia orofacial induzida por reserpina em camundongos e atividade damonoaminoxidase
(Universidade Federal de Santa Maria, 2018-03-20)
Tardive dyskinesia (TD) is a disabling and debilitating disorder due to the chronic use of antipsychotics that affects around 20% to 50% of patients. It is characterized by involuntary, repetitive and abnormal movements ...
Efeito toxicogenético do polimorfismo Ala16Val do gene MnSOD em leucócitos expostos in vitro ao metil mercúrio
(Universidade Federal de Santa Maria, 2012-03-19)
The environmental contamination by methyl mercury (MeHg) is a great health public problem in
some world regions like Amazonia. The MeHg toxic effects seem to be influenced by
environmental and genetic factors. However, ...
Efeito da rutina e da curcumina em marcadores inflamatórios e oxidativos em modelo experimental de hiperlipidemia
(Universidade Federal de Santa Maria, 2019-02-28)
Hyperlipidemia is characterized by lipid abnormalities that result in inflammation and
oxidative damage, factors involved in the development of atherosclerosis. Adenosine and
adenosine deaminase (ADA) modulate ...
Contribuição do sistema colinérgico e da sinalização do NRF2/HO-1 para a ação anti-amnésica do 7-flúor-1,3- difenilisoquinolina-1-amina em camundongos
(Universidade Federal de Santa Maria, 2019-07-26)
Dementia is a heterogenic condition characterized by different symptoms and theories about its pathogenesis, which results in difficult to understand and in the treatment of this disease. The 7-fluoro-1,3-diphenylisoquin ...
Efeito anti-inflamatório do ácido cafeico sobre o sistema purinérgico e colinérgico em ratos Diabéticos tipo 1
(Universidade Federal de Santa Maria, 2020-02-27)
Diabetes mellitus (DM) is a metabolic disorder, considered one of the biggest public health problems in the world. This disease is characterized by a state of chronic hyperglycemia that leads to metabolic disorders. Studies ...
Atividade antitumoral da berberina em células de neuroblastoma SH-SY5Y
(Universidade Federal de Santa Maria, 2017-02-23)
Neuroblastoma is the most common tumor found in the first year of life and represent 6% of the all childhood cancers. There is few options of treatment and the mortality is close to 21%, or exceeds 50% between the high ...
Investigação e comparação dos efeitos tóxicos iduzidos por etil e metilmercúrio: Drosophila melanogaster como organismo modelo
(Universidade Federal de Santa Maria, 2020-03-13)
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Associação do disseleneto de difenila e moduladores do sistema glutamatérgico frente ao dano oxidativo causado por ácido quinolínico
(Universidade Federal de Santa Maria, 2013-02-22)
Excessive formation of reactive oxygen species (ROS) and disruption of glutamate
uptake have been hypothesized as key mechanisms contributing to quinolinic acid (QA)-
induced toxicity. Thus, here we investigate if the ...
Efeito do decocto de Bauhinia forficata sobre parâmetros comportamentais e metabólicos em ratos tratados com haloperidol
(Universidade Federal de Santa Maria, 2012-09-27)
Schizophrenia is a psychiatric disorder that affects 1% of world population and its pharmacologic treatment consists in the use of antipsychotics. It is known that chronic treatment with classical antipsychotics, such as ...
Atividade de ectoenzimas e de colinesterases e biomarcadores de estresse oxidativo em pacientes com câncer de pulmão
(Universidade Federal de Santa Maria, 2012-03-02)
Lung cancer has become one of the most commonly diagnosed neoplastic diseases, as well as one of the most lethal worldwide, characterized, therefore, as a public health problem. This spread of lung cancer in the world ...