Prevalência e medidas empregadas para o controle da mucosite oral induzida pelo uso de antineoplásicos em Centro de Transplante de Medula Óssea

Abstract

The oral mucositis (OM) resulting from the use of anticancer drug is one of the most common adverse events in patients undergoing bone marrow transplantation, and whose severity in some cases leads to suspension of treatment thereby its prognosis. The aim of our study was to identify the prevalence and the measures employed to control oral mucositis induced by the use of antineoplastic agents on Bone Marrow Transplant Center (BMTC) of the University Hospital of Santa Maria (UHSM), Santa Maria-RS. This research was carried out through retrospective analysis of patient records in the period between transplants performed January 2009 and October 2011. The OM occurred in 95.5%. The most common drugs used were the filgrastim, cyclophosphamide, cyclosporine A and busulfan. The therapeutic measures conducted in 71.12 % of OM instances. Recommend measures to improve oral hygiene with possible inclusion of low intensity laser therapy or photodynamic therapy.