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Agentes poliaminérgicos modulam a reconsolidação da memória de medo em ratos
(Universidade Federal de Santa Maria, 2013-08-19)
The memory may be studied according with memory's phases, which is acquisition, consolidation and recall. Memories once consolidated, are no more susceptible to interventions, but when reactivated, some of these memories ...
Perfil lipidíco, agregação plaquetária e atividade de ectoenzimas do sistema purinérgico em plaquetas de pacientes HIV positivos sob terapia antirretroviral
(Universidade Federal de Santa Maria, 2013-08-23)
HIV infection is characterized by continuous viral replication and depletion of
CD4 + T lymphocytes, leading to immunological changes and opportunistic
infections by pathogens. The use of antiretroviral therapy (ART) ...
Avaliação da capacidade antioxidante in vitro de novos compostos mono e disseleneto
(Universidade Federal de Santa Maria, 2013-07-26)
The antioxidant action of organic selenium compounds, as well as ebselen and diphenyl diselenide (DPDS), is closely connected to its ability of generating the selenol group. (In) this study it was evaluated the in vitro ...
Estudo das propriedades antioxidantes de diferentes ftalocianinas
(Universidade Federal de Santa Maria, 2013-02-22)
Oxidative stress is believed to be involved in the etiology of several chronic diseases, including cardiovascular disease, diabetes, cancer, and neurodegenerative disorders. From this perspective, we have evaluated the ...
Associação do disseleneto de difenila e moduladores do sistema glutamatérgico frente ao dano oxidativo causado por ácido quinolínico
(Universidade Federal de Santa Maria, 2013-02-22)
Excessive formation of reactive oxygen species (ROS) and disruption of glutamate
uptake have been hypothesized as key mechanisms contributing to quinolinic acid (QA)-
induced toxicity. Thus, here we investigate if the ...
Efeito protetor do extrato hidroalcoólico de própolis marrom nas lesões vaginais induzidas pelo herpes simples vírus tipo 2
(Universidade Federal de Santa Maria, 2013-01-25)
Propolis is a natural compound and has been highlighted for its antioxidant, antiinflammatory
and antiviral properties. The purpose of this study was to investigate if
brown hydroalcoholic propolis extract (HPE) protects ...
Efeito da espermidina sobre a persistência da memória em ratos
(Universidade Federal de Santa Maria, 2013-02-22)
The long-term memory involves three stages: acquisition, consolidation and extinction. However was recently described a new phase of consolidation, called the persistence of memory. At this stage, crucial events occur 12 ...
Efeito do guaraná (Paullinia cupana) no metabolismo de nucleotídeos e nucleosídeo de adenina em um modelo experimental de hipercolesterolemia
(Universidade Federal de Santa Maria, 2013-08-09)
Hypercholesterolemia is a metabolic disease characterized by high levels of serum low density lipoproteins and total cholesterol, associated with the inflammatory disorders, the migration of monocytes and T cells and with ...
Envolvimento do sistema dopaminérgico na ação do tipo antidepressiva do fenilselenometil em camundongos fêmeas
(Universidade Federal de Santa Maria, 2013-08-05)
Depression affects millions of people of different ages, races, religions and income at some period of their lives. The etiology of most mood disorders, although not fully understood, has come into sharper focus in the ...
Avaliação da capacidade do disseleneto de difenila em reduzir a falência hepática aguda induzida por paracetamol em camundongos
(Universidade Federal de Santa Maria, 2013-09-18)
Paracetamol (APAP) is commonly used analgesic and antipyretic, however high doses can induce damage hepatic. The metabolic N-acetyl-p-benzoquinone imine (NAPQI) is responsible for the toxic effects. The accumulation of ...