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Aumento da suscetibilidade ao pentilenotetrazol após a sobrevivência de um quadro de malária cerebral em camundongos
(Universidade Federal de Santa Maria, 2017-07-10)
Malaria is considered a neglected disease and public health problem, affecting more than 200 million people worldwide. Plasmodium falciparum, one of the four human parasitic species, is responsible for the development of ...
O papel da amônia sobre as alterações comportamentais, neuroinflamação e apoptose em um modelo experimental de acidemia metilmalônica.
(Universidade Federal de Santa Maria, 2017-08-29)
Methylmalonic acidemia is an autosomal recessive metabolism biochemically characterized by
a deficiency in the activity of the mutase methylmalonyl-CoA and the tissue accumulation of
methylmalonate (MMA). In this acidemia, ...
Associação da via inflamatória e apoptótica na patofisiologia do acidente vascular encefálico tardio: relação com a dislipidemia
(Universidade Federal de Santa Maria, 2015-01-22)
Stroke occurs when blood flow to the brain is interrupted by an embolic or thrombotic occlusion of a cerebral artery (ischemic stroke) or by bleeding from a ruptured blood vessel (hemorrhagic stroke). Oxidative stress and ...
Efeito farmacogenético do polimorfismo Ala16Val do gene da MnSOD na resposta de pacientes hipercolesterolêmicos a rosuvastatina
(Universidade Federal de Santa Maria, 2015-02-27)
Rosuvastatin is used as a drug of first choice in treating hypercholesterolemia due to
competitive inhibition of HMG-CoA reductase enzyme which converts HMG-CoA to
mevalonic acid which is the rate-limiting step in ...
Caracterização molecular de enterobactérias resistentes aos carbapenêmicos
(Universidade Federal de Santa Maria, 2014-04-30)
Enterobacteriaceae resistant to carbapenems cause great impact on public health due to their different evolutionary mechanisms of resistance. The mechanism of resistance that recently has been reported in Enterobacteriaceae ...
Atividade imunomoduladora de células dendríticas pulsadas com antígenos de Pythium insidiosum sobre a resposta celular in vitro
(Universidade Federal de Santa Maria, 2016-03-15)
Pythiosis is a severe disease caused by the Oomycete Pythium insidiosum which can affect
animals and humans. If not diagnosed and immediately treated, pythiosis can lead the affected
host to death. Pythiosis treatment ...
Avaliação dos efeitos de um campo magnético pulsado sobre a cicatrização cutânea e biomarcadores oxidativos em ratos wistar
(Universidade Federal de Santa Maria, 2015-08-14)
The surgical postoperative period requires rapid, effective and good-quality wound repair. For a better cicatrization process alternatives have been sought to assist wound repair and improve the appearance of scarred region. ...
Terapia de emissão de luz por diodo induz analgesia em modelos de nocicepção em camundongos: análise do mecanismo de ação
(Universidade Federal de Santa Maria, 2015-09-04)
The LEDT is a fairly recent category of phototherapy and there is evidence that accelerates wound healing, reduce inflammation and painful. However, there are few scientific studies on the action mechanisms of LEDT in pain ...
Investigação da presença e migração de metais presentes em estabilizantes e catalisadores em embalagens plásticas
(Universidade Federal de Santa Maria, 2015-03-16)
The polyvinyl chloride (PVC) and polyethylene terephthalate (PET) polymers are widely used throughout the world. Different types of compounds are used in the polymer synthesis and to improve their properties. In the case ...
Efeito da morfina sobre a persistência da memória de medo condicionado contextual em ratos
(Universidade Federal de Santa Maria, 2015-01-16)
It is established that opioids modulate brain networks involved in learning and memory. Studies using various learning tasks have shown that morphine impairs many forms of memory. A common feature of these studies is that ...