Potencial antioxidante de extrato de cevada em ratos submetidos à dieta hiperlipídica

Abstract

The oxidative stress is an imbalance between reactive oxygen species and the antioxidants action capacity, which cause cellular injury, triggering and exacerbating some pathologies. Thus, researchs, seek to alternative to ease damaging effects of oxidative stress, improving the body's antioxidant capacity, which can be an alternative for the treatment and prevention of diseases and its complications. The polyphenols belong to a class of phytochemicals that show a strong antioxidant role. The barley is a cereal rich in polyphenols, can inhibit the oxidation of lipoproteins, reducing the damages of oxidative stress. This work aimed to study the effect of the extract of barley on lipid oxidation in rats subjected to high-fat diet. The experiment was conducted over a period of 67 days, where the animals were submitted to a diet rich in pork fat, one of the experimental groups supplemented with barley extract. We assessed the body weight gain and food consumption were performed biochemical analysis of serum and the malondialdehyde was quantified in liver tissue. There were no differences in weight gain and biochemical parameters of the animals. Experimentally, the barley extract reduced lipid peroxidation in the liver of mice, caused by high-fat diet, so barley is a cereal rich in polyphenols, and its extract is an effective antioxidant.