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Atividade hipolipidêmica do disseleneto de difenila na hiperlipidemia induzida por Triton WR-1339 em camundongos
(Universidade Federal de Santa Maria, 2009-11-26)
In mammals, the liver plays a central role in whole-body lipid metabolism. Unfortunately, dysregulation of these pathways has been implicated in hyperlipidemias. In recent years, a significant association between the trace ...
Vitamina C plasmática está negativamente associada com a atividade das aminotransferases em pacientes com hepatite C não tratados
(Universidade Federal de Santa Maria, 2007-04-20)
In this study, the possible relationship between aminotransferase activities and markers of oxidative stress in hepatitis C patients was evaluated. Patients with HCV
(hepatitis C virus) infection confirmed by positive HCV ...
Cisplatina induz um padrão de toxicidade hepatorrenal diferente em ratos neonatos e adultos
(Universidade Federal de Santa Maria, 2018-07-20)
Cisplatin is a widely used chemotherapeutic to treat several types of tumors on both adult and pediatric subjects. Although cisplatin is widely used, its use is associated with serious toxic effects, including nephrotoxicity ...
Papel do magnésio na prevenção e reversão de distúrbios motores experimentalmente induzidos
(Universidade Federal de Santa Maria, 2014-10-31)
Chronic treatment of psychotic disorders is associated with adverse effects that affect
motor function. Movement disorders include Parkinsonism, akathisia, dystonia and tardive
dyskinesia. Magnesium (Mg) is an essential ...
Neuroinflamação e via apoptótica na epilepsia
(Universidade Federal de Santa Maria, 2015-02-09)
Epilepsy is a neurological disease that affects around 1% of world population, with neurobiological, neurochemical, cognitive and psychological consequences. Despite the good prognosis, the high number of epilepsy patients ...
Efeito da toxicidade do alumínio sobre a resposta antioxidante endógena em três genótipos de aveia
(Universidade Federal de Santa Maria, 2016-08-10)
Aluminum (Al) is a metal that presents toxic effect on plant growth in acidic soils. In these soils, with pH under 5.5, Al can be found in its trivalent form (Al3+), which might compromise the root growth, as well as affect ...
Influência dos diferentes ácidos graxos da dieta sobre um modelo animal de mania induzido por anfetamina em ratos
(Universidade Federal de Santa Maria, 2010-04-22)
Fatty acids (FA) are constituent important of the neuronal phospholipids membranes and they carry out important functions in the development and function of the brain During the last decades changes were observed in the ...
Ingestão da tintura de valeriana officinalis protege da discinesia orofacial induzida por reserpina em ratos
(Universidade Federal de Santa Maria, 2009-04-15)
Considering the hypothesis that GABA and oxidative stress are involved in the development of oral movements associated with important neuropathologies, the present
study investigated the possible ability of V. officinalis ...
Exposição simultânea ao vinilciclohexeno e ao metilmercúrio em Drosophila melanogaster: análise bioquímica e molecular
(Universidade Federal de Santa Maria, 2017-02-13)
Exposition to toxic compounds is becoming more frequent. This fact is of relevant since xenobiotics cause an imbalance in the body homeostasis mainly inducing oxidative stress. In addition, they can alter enzyme activities ...
Efeitos do exercício físico sobre parâmetros de estresse oxidativo em ratos hipertensos
(Universidade Federal de Santa Maria, 2011-09-05)
Hypertension has been regarded as one of the most important factors associated with the
development of vascular disease and is closely linked to increased reactive oxygen species (ROS). In
contrast, exercise has been ...