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Avaliação dos efeitos biológicos do (s) (3-feniltelanil propanamida) succinato de dimetila, um novo telúrio aminoácido derivado do ácido aspártico
(Universidade Federal de Santa Maria, 2011-03-25)
Recent studies from our group demonstrated that the (S)-dimethyl 2-(3-(phenyltellanyl) propanamido) succinate compound, a telluroamino acid showed glutathione peroxidase (GPx)-like activity, attesting to its antioxidant ...
Aplicação de disseleneto de difenila subcutâneo em camundongos infectados com Toxoplasma gondii: efeitos imunomodulatórios e antioxidantes
(Universidade Federal de Santa Maria, 2017-07-14)
Toxoplasma gondii é capaz de parasitar qualquer tipo de célula nucleada, podendo causar alterações bioquímicas, funcionais e estruturais nas células dos hospedeiros. Os quimioterápicos para o tratamento não são totalmente ...
Análise das propriedades antioxidantes das oximas 3-(fenil hidrazona) butano-2-ona e butano-2,3-dionatiosemicarbazona
(Universidade Federal de Santa Maria, 2008-05-12)
Oximes are chemical compounds used to reactivate the inhibited acetylcholinesterase (AChE) enzyme by organophosphates (OPs). The OPs, besides classically recognized as AChE irreversible inhibitors, are also involved in the ...
Artemísia absinthium minimiza a toxicidade induzida por paracetamol em camundongos
(Universidade Federal de Santa Maria, 2015-09-22)
Acetaminophen is a popular analgesic associated with toxic ingestions. There are many studies about prevention of APAP induced hepatotoxicity including the medicinal plants. Artemisia absinthium (AA) is one of them, but ...
Efeitos do ácido gálico em parâmetros bioquímicos e de estresse oxidativo em ratos submetidos a um modelo experimental de diabetes
(Universidade Federal de Santa Maria, 2015-09-11)
Diabetes mellitus (DM) is a metabolic disorder characterized by hyperglycemia associated with the increase of free radicals and decrease in the antioxidant response. Gallic acid has many biological properties, among them ...
Efeitos do disseleneto de difenila em carpas expostas a uma formulação comercial contendo cipermetrina e clorpirifós
(Universidade Federal de Santa Maria, 2016-03-11)
Agricultural activity is one of the main factors that lead to the increase of contaminants in aquatic ecosystems and may cause oxidative stress in fish. The objective of this work was to verify the protective effects of ...
Efeito do ácido cafeico e ácido cafeico fenetil éster em modelo de inflamação induzida por lipopolisacarídeo
(Universidade Federal de Santa Maria, 2016-08-05)
Peripheral inflammation is able to cause alterations in central nervous system (CNS) and lead to progression of neurodegenerative diseases. During neuroinflammatory process the activation of immune cells from the CNS and ...
Efeito da (+)-catequina sobre adiscinesia orofacial induzida por reserpina em camundongos e atividade damonoaminoxidase
(Universidade Federal de Santa Maria, 2018-03-20)
Tardive dyskinesia (TD) is a disabling and debilitating disorder due to the chronic use of antipsychotics that affects around 20% to 50% of patients. It is characterized by involuntary, repetitive and abnormal movements ...
Avaliação da capacidade antioxidante in vitro de novos compostos mono e disseleneto
(Universidade Federal de Santa Maria, 2013-07-26)
The antioxidant action of organic selenium compounds, as well as ebselen and diphenyl diselenide (DPDS), is closely connected to its ability of generating the selenol group. (In) this study it was evaluated the in vitro ...
Efeito protetor do extrato hidroalcoólico de própolis marrom nas lesões vaginais induzidas pelo herpes simples vírus tipo 2
(Universidade Federal de Santa Maria, 2013-01-25)
Propolis is a natural compound and has been highlighted for its antioxidant, antiinflammatory
and antiviral properties. The purpose of this study was to investigate if
brown hydroalcoholic propolis extract (HPE) protects ...