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Respostas bioquímicas em carpas (Cyprinus carpio) expostas ao fungicida tebuconazole (folicur® 200 ec)
(Universidade Federal de Santa Maria, 2010-07-22)
The intensive use and/or inadequate management of pesticides have led to contamination of the aquatic ecosystem, reaching the biota living there, including the fish. Pesticides can affect toxicological parameters these ...
Efeito da exposição in vivo ao ditelureto de difenila em camundongos: evidências para estresse oxidativo
(Universidade Federal de Santa Maria, 2010-09-24)
In this work, we investigated the effect of (PhTe)2 administration (10 μmol/kg and 50 μmol/kg) to adult mice on the behavioral performance and on some parameters of oxidative stress in the brain ad liver. The animals ...
Efeito in vitro do polimorfismo ala16val do gene da superóxido dismutase dependente de manganês no metabolismo oxidativo de linfócitos
(Universidade Federal de Santa Maria, 2010-03-05)
Epidemiological studies suggest that the imbalance in antioxidant enzymes activity genetically caused, increases the risk of metabolic disorders and chronic noncommunicable
diseases. This is the case of polymorphism that ...
Efeitos do mercúrio sobre a atividade das enzimas alanina aminotransferase, lactato desidrogenase e glicose 6-fosfatase de ratos jovens
(Universidade Federal de Santa Maria, 2010-03-25)
Mercury is an environmental contaminant, and may accumulate in living organisms causing several damage. Studies have shown that this metal causes several physiological and biochemical alterations in young rats which are ...
Atividade de enzimas que hidrolisam nucleotídeos de adenina em plaquetas de pacientes com artrite reumatóide
(Universidade Federal de Santa Maria, 2010-03-26)
Rheumatoid arthritis (RA) is a chronic inflammatory disease autoimmune of unknown etiology. Patients with RA have a lower survival than the general population, the most
common cause of mortality in these patients is ...
Efeitos bioquímicos e fisiológicos do chumbo em plantas de quitoco (Pluchea sagittalis): possível papel fitorremediador
(Universidade Federal de Santa Maria, 2010-02-18)
Lead (Pb) is one of the most abundant, globally distributed toxic elements. Soil, water and air contamination by Pb leads to its accumulation in fish, mammals, and plants, and thus to human intoxication through food. Due ...
Efeito antioxidante de uma nova classe de compostos teluroacetilenos: estudos in vitro e in vivo
(Universidade Federal de Santa Maria, 2010-04-01)
Organotellurium compounds have been reported as antioxidants in several models of oxidative stress, especially in the brain. This study investigated the effect of telluroacetylenes a-d on pharmacological assays in vitro. ...
Eriodictiol: um flavonóide antagonista do receptor TRPV1 com atividade antioxidante
(Universidade Federal de Santa Maria, 2010-08-13)
The transient receptor potential vanilloid 1 (TRPV1) is a calcium permeable channel responsible for the transduction and modulation of acute and chronic pain signaling, being a potential target for treatment of different ...
Avaliação do envolvimento da enzima monoamina oxidase B em modelos de dor pós-operatória e neuropática em camundongos
(Universidade Federal de Santa Maria, 2010-03-26)
Monoamines appear to play an important modulatory role on pain descending pathways and are involved in the antinociceptive mechanism of several drugs commonly used for the management of pain. In this study, we assessed the ...
Efeito do tipo antidepressivo do disseleneto de difenila em um modelo de depressão induzida por malation em ratos
(Universidade Federal de Santa Maria, 2010-04-01)
Organophosphorus (OP), among them malathion, are responsible for most of the poisonings reported annually in Brazil. In addition to symptoms of cholinergic
poisoning, the exposure to OP causes affective and cognitive ...