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Efeitos do disseleneto de difenila na atividade da enzima δ-aminolevulinato desidratase e em parâmetros bioquímicos de ratos com diabetes mellitus tipo 1
(Universidade Federal de Santa Maria, 2004-07-16)
The hyperglycemia and oxidative stress are factors strongly involved on development of many disorders that characterize the Diabetes Mellitus. It is known that some organic and inorganic selenium compounds are potent ...
Os efeitos de organocalcogêneos e de 2,3-dimercaptopropanol sobre convulsão química e letalidade induzidas por pentilenotetrazol e 4-aminopiridina em camundongos
(Universidade Federal de Santa Maria, 2007-08-17)
Experimental models of seizure in animals have represented an important role for the understanding of the physiological and behavioural alterations associated with the human epilepsy. The induction of partial or generalized ...
Atividade hipolipidêmica do disseleneto de difenila na hiperlipidemia induzida por Triton WR-1339 em camundongos
(Universidade Federal de Santa Maria, 2009-11-26)
In mammals, the liver plays a central role in whole-body lipid metabolism. Unfortunately, dysregulation of these pathways has been implicated in hyperlipidemias. In recent years, a significant association between the trace ...
Efeito de antioxidantes sobre os níveis de metalotioneínas em camundongos tratados com cloreto de mercúrio
(Universidade Federal de Santa Maria, 2006-02-23)
In this study, acute effects of mercury on mouse blood, kidneys and liver were evaluated. Mice received a single dose of mercuric chloride (HgCl2 - 4.6 mg/kg, subcutaneously) for three consecutive days. We investigated the ...
Efeitos da exposição materna ou paterna ao disselento de difenila sobre o desenvolvimento intra-uterino da prole de ratas wistar
(Universidade Federal de Santa Maria, 2006-07-27)
Selenium (Se) is an essential trace element for man and is known for its role in regulating growth and development of the fetus and newborn. Furthermore, Se is a micronutrient required for normal spermatogenesis and, ...
Envolvimento do estresse oxidativo nas convulsões induzidas por disseleneto de difenila em ratos jovens
(Universidade Federal de Santa Maria, 2007-08-01)
Seizures can occur at any age, affecting at least 1-2% of the world population, they are far more common in children than adults. Prolonged seizures in the early developmental period can cause brain damage and lead to ...
Avaliação dos efeitos do tratamento crônico com neurolépticos e sua interação com substâncias potencialmente antioxidantes sobre parâmetros de estresse oxidativo no fígado e rim de ratos
(Universidade Federal de Santa Maria, 2008-03-27)
Treatment with neuroleptic drugs has been associated to side effects like tardive diskynesia and hepatic damage. In spite of the several reports of hepatotoxicity after neuroleptic administration, few data are available ...