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Isolamento do principal constituinte ativo do óleo essencial de Lippia alba (Mill.) N. E. Brown com potencial anestésico geral e estudo do mecanismo de ação
(Universidade Federal de Santa Maria, 2011-01-24)
Lippia alba (Mill.) N. E. Brown is an aromatic herb commonly used as sedative and
for the treatment of gastrointestinal disturbs. Many literature data confirm the
sedative property of the essential oil (EO) of this ...
Influência farmacogenética da enzima SOD2 na resposta in vitro ao resveratrol de células mononucleares
(Universidade Federal de Santa Maria, 2014-10-03)
Resveratrol (RES) is an anti-aging molecule that provides both anti-inflammatory and antioxidant properties. However, it is unclear whether the basal oxidative state of the cell has any influence on the effects of this ...
Influência do polimorfismo Ala16Val do gene da enzima superóxido dismutase (SOD2) no efeito antioxidante in vitro do citrato de clomifeno
(Universidade Federal de Santa Maria, 2011-08-16)
To investigate the in vitro antioxidant properties of the ovulation induction drug,
Citrate clomiphene (CC), and to access whether its effects are influenced by the
Ala16Val polymorphism in the SOD2 gene, which encodes ...
Influência da temperatura na ação do fungo Duddingtonia flagrans utilizado como controle biológico de Haemonchus contortus em ovinos
(Universidade Federal de Santa Maria, 2010-05-28)
In recent years has increased the search for alternative methods to combat
gastrointestinal parasites, and in this context, biological control achieved by the fungus
Duddingtonia flagrans draws attention. In this study, ...
Função da ocitocina na indução da retomada meiótica de oócitos em bovinos
(Universidade Federal de Santa Maria, 2011-10-31)
The aim of the present study was to examine the role of oxytocin (OT) on the control of oocyte meiotic resumption in the events that involves progesterone (P4) and prostaglandins (PGs). Oocytes were co-cultured with ...
Frutose-1,6-bisfosfato e N-acetilcisteína atenuam a formação de produtos proteicos de oxidação avançada, uma nova classe de mediadores inflamatórios, in vitro
(Universidade Federal de Santa Maria, 2012-09-19)
The assessment of biomarkers of reactions involving reactive oxygen species have the
potential not only to determine the extent of oxidative damage, but also to predict the
effectiveness of therapeutic strategies aimed ...
Efeito cito-genômico do peróxido de hidrogênio e do guaraná (Paullinia cupana) em células tronco mesenquimais
(Universidade Federal de Santa Maria, 2014-01-22)
With advances in techniques of cell culture, stem cells (SCs) have to be used as an alternative therapy, firming the called regenerative medicine. An type of SC that has been studied is the Adipose-derived stem cell (ASCs) ...
Efeito da administração oral de aflatoxina B1 nas convulsões induzidas em ratos
(Universidade Federal de Santa Maria, 2014-08-14)
Aflatoxins are produced by Aspergillus flavus fungi, mainly A. parasiticus and A. nomius. Aflatoxin B1 (AFB1) is the most common and highly toxic mycotoxin, presents carcinogenic, mutagenic and teratogenic effects. This ...
Efeito da cafeína sobre a consolidação tardia da memória de medo em ratos
(Universidade Federal de Santa Maria, 2016-07-19)
Caffeine, an antagonist of adenosine receptors, is one of the most widely consumed psychostimulant substance in the world. There are contradicting reports about the effect of caffeine on learning and memory. While some ...
Traxoprodil atenua as convulsões induzidas por pentilenotetrazol
(Universidade Federal de Santa Maria, 2010-09-23)
There is evidence that while polyamines facilitate seizures by positively modulating N-methyl-D-aspartate receptors (NMDAr), selective antagonists of the NR2B-subunit decrease seizures. However, it remains undetermined ...