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Efeito cito-genômico do peróxido de hidrogênio e do guaraná (Paullinia cupana) em células tronco mesenquimais
(Universidade Federal de Santa Maria, 2014-01-22)
With advances in techniques of cell culture, stem cells (SCs) have to be used as an alternative therapy, firming the called regenerative medicine. An type of SC that has been studied is the Adipose-derived stem cell (ASCs) ...
Efeito da administração oral de aflatoxina B1 nas convulsões induzidas em ratos
(Universidade Federal de Santa Maria, 2014-08-14)
Aflatoxins are produced by Aspergillus flavus fungi, mainly A. parasiticus and A. nomius. Aflatoxin B1 (AFB1) is the most common and highly toxic mycotoxin, presents carcinogenic, mutagenic and teratogenic effects. This ...
Efeito da cafeína sobre a consolidação tardia da memória de medo em ratos
(Universidade Federal de Santa Maria, 2016-07-19)
Caffeine, an antagonist of adenosine receptors, is one of the most widely consumed psychostimulant substance in the world. There are contradicting reports about the effect of caffeine on learning and memory. While some ...
Traxoprodil atenua as convulsões induzidas por pentilenotetrazol
(Universidade Federal de Santa Maria, 2010-09-23)
There is evidence that while polyamines facilitate seizures by positively modulating N-methyl-D-aspartate receptors (NMDAr), selective antagonists of the NR2B-subunit decrease seizures. However, it remains undetermined ...
Efeito in vitro da suplementação do guaraná (Paullinia cupana) na atividade de quimioterápicos usados no tratamento do câncer de mama
(Universidade Federal de Santa Maria, 2014-01-24)
Cancer related fatigue (CRF) is a common phenomenon in patients undergoing chemotherapy and radiotherapy representing a negative impact on functional status and quality of life. Some plants present tonic and antifatiguing ...
Efeito farmacogenético e farmacogenômico do metotrexato na citotoxicidade de células mononucleares periféricas do sangue
(Universidade Federal de Santa Maria, 2014-07-18)
Methotrexate (MTX) is an antimetabolite drug analogue of folic acid with wide clinical application, used in high doses for the treatment of cancer and in low doses for the treatment of autoimmune diseases such as rheumatoid ...
Efeito do Hypericum perforatum em diferentes modelos de desordens motoras em ratos
(Universidade Federal de Santa Maria, 2013-02-26)
Abnormal movements are clinical symptoms present in neurodegenerative diseases, such
Parkinsonism , as well as Tardive dyskinesia. It is thought that unbalance in monoamine
levels with their consequent metabolism could ...
Efeito do óleo essencial de lippia alba nos parâmetros oxidativos do jundiá (Rhamdia quelen) exposto a diferentes concentrações de oxigênio
(Universidade Federal de Santa Maria, 2009-09-01)
Juvenile silver fish (Rhamdia quelen) were exposed to the essential oil of
Lippia alba (L. alba) and transported in plastic bags for different periods (5, 6 and 7
h) yielding final different oxygen levels. The biomarkers ...
Efeito do Harpagophytum procumbens sobre parâmetros de estresse oxidativo e a viabilidade celular in vitro
(Universidade Federal de Santa Maria, 2013-10-04)
Harpagophytum procumbens, known as devil's claw, is an African plant with numerous therapeutic effects, among which stands out for its powerful anti-inflammatory action, but the mechanism by which exerts its effect is not ...
Efeito de dose única de vitamina D nas concentrações séricas de citocinas em mulheres idosas na pós-menopausa
(Universidade Federal de Santa Maria, 2014-03-07)
Vitamin D is an important immunomodulator. Epidemiological studies have shown that vitamin D deficiency impairs the immune functions and participates in the pathogenesis of infectious and autoimmune diseases. Vitamin D ...